Rabbit Anti-TAG-72/CA72.4 Antibody MBS4380844 from MyBioSource.com

Product Specs
ItemRabbit Anti-TAG-72/CA72.4 Antibody
CompanyMyBioSource.com
Price $190.00Supplier Page View Company Product Page
Catalog NumberMBS4380844
Quantity0.02 mg (With BSA & Azide at 0.2mg/ml)
ClonalityMonoclonal
ReactivityHuman, Cow, Dog, Hamster, Rat
Format200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml
ApplicationsImmunohistochemistry (IHC) Paraffin
SpeciesRabbit
Molecular Weight220kDa
TargetTAG-72/CA72.4 (Tumor-Associated Glycoprotein)
PurityPurified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Conjugate/TagUnconjugated
IsotypeIgG
CloneCA72/2869R

Specifications/Features

Recognizes an oncofetal antigen of 220kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This MAb defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80% sensitivity and 93% specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of anti-TAG-72 and anti-GCDFP-15 is valuable in the diagnosis of apocrine carcinoma

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