Human/Rat GFAP Antibody AF2594 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemHuman/Rat GFAP Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $499.00Supplier Page View Company Product Page
Catalog NumberAF2594
Quantity100 ug (also 25 ug)
ApplicationsImmunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Simple Western,Immunocytochemistry
Conjugate/TagUnconjugated
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ConcentrationLYOPH
PurityAntigen Affinity-purified
TargetGFAP
ReactivityHuman,Mouse,Rat
HostSheep
IsotypeIgG
Antibody TypePrimary Antibodies
NCBI Full Gene Nameglial fibrillary acidic protein
ClonalityPolyclonal
ImmunogenE. coli-derived recombinant human GFAP, Leu292-Met432, Accession # P14136
NCBI Gene AliasesALXDRD
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Unconjugated

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Endoplasmic Reticulum Stress Drives Neuroinflammation Through Lipocalin 2 Upregulation in Retinal Microglia After Optic Nerve InjuryInvestigative ophthalmology & visual scienceMay 1, 2025Huang W, Liu Y, Li J, Gao Y, Tang J, Yip S, Wang X, Zhang H, Ma Y, Su S, et al.primary antibodies: LCN2 (1:200, AF1857; R&D Systems), Iba1 (1:200, ab178846; Abcam), GFAP (1:100, AF2594; R&D Systems), and Tuj1 (1:250, 801202; BioLegend, San Diego, California, USA). Sections were subsequently

(2) Dengue Virus Infection of Human Retinal Müller Glial CellsVirusesJune 21, 2023Oliver GF, Ashander LM, Dawson AC, Ma Y, Carr JM, Williams KA, Smith JR.IgG anti-human glial fibrillary acidic protein (R&D Systems, Minneapolis, MN, USA, catalogue number: AF2594, working concentration: 10 µg/mL), or a relevant negative control antibody in matched concentration,

(3) A single-cell transcriptome atlas of glial diversity in the human hippocampus across the postnatal lifespanCell stem cellNovember 3, 2022Su Y, Zhou Y, Bennett ML, Li S, Carceles-Cordon M, Lu L, Huh S, Jimenez-Cyrus D, Kennedy BC, Kessler SK, et al.Cd83 (mouse, Bio-rad, MCA1582, 1:50), Cd83 (mouse, BioLegend, 305302, 1:50), Gfap (sheep, R&D Systems, AF2594, 1:1000), Iba1 (rabbit, WAKO, 019–19741, 1:500), Olig2 (goat, R&D Systems, AF2418, 1:500), S100b (rabbit,

(4) Modeling the mature CNS: A predictive screening platform for neurodegenerative disease drug discoveryJournal of neuroscience methodsJuly 1, 2021LaBarbera KM, Limegrover C, Rehak C, Yurko R, Izzo NJ, Knezovich N, Watto E, Waybright L, Catalano SM.AB_1977159,Polyclonal,Rabbit Anti-Glial fibrillary acidic protein (GFAP),2 μg/mL,R&D Systems Cat # AF2594; RRID: AB_2109656,Polyclonal,Sheep Anti-Microtubule associated protein 2 (MAP2),0.2 μg/mL,Millipore Sigma

(5) Sigma-2 receptor antagonists rescue neuronal dysfunction induced by Parkinson's patient brain-derived α-synucleinJournal of neuroscience researchApril 1, 2021Limegrover CS, Yurko R, Izzo NJ, LaBarbera KM, Rehak C, Look G, Rishton G, Safferstein H, Catalano SM.glial fibrillary acidic protein (GFAP; 1:500, 0.2 mg/ml, R&D Systems, Minneapolis, MN, USA, catalog number AF2594, RRID:AB_2109656) with labeled projections coming from the cell bodies, with the remainder likely microglia. 2.2

(6) Anti-Müllerian Hormone Regulation of Synaptic Transmission in the Hippocampus Requires MAPK Signaling and Kv4.2 Potassium Channel ActivityFrontiers in neuroscienceJanuary 1, 2021Wang K, Xu F, Maylie J, Xu J.NA10098717; Novus Biologicals, Centennial, CO, United States), glial fibrillary acidic protein (GFAP; AF2594; R&D Systems, Minneapolis, MN, United States), and ionized calcium binding adaptor molecule 1 (IBA1;

(7) Methamphetamine leads to the alterations of microRNA profiles in the nucleus accumbens of ratsPharm BiolDecember 1, 2020Yang J, Li L, Hong S, Zhang D, Zhou Y.(neuron specific enolase, catalog No. AF5169) and GFAP (glial fibrillary acidic protein, catalog No. AF2594) was obtained from the R&D system (Minneapolis, MN, USA). Then, the sections were rinsed 3 times with

(8) Proneurotrophins Induce Apoptotic Neuronal Death After Controlled Cortical Impact Injury in Adult MiceASN neuroJanuary 1, 2020Montroull LE, Rothbard DE, Kanal HD, D'Mello V, Dodson V, Troy CM, Zanin JP, Levison SW, Friedman WJ.RRID:AB_2039758), anti-glial fibrillary acidic protein (GFAP; 1:500; R&D Systems, Minneapolis, MN, USA, Cat# AF2594, RRID:AB_2109656), and anti-p75NTR (1:500; R&D Systems, Cat# AF1157, RRID:AB_2298561). Western Blot Tissue

(9) APP upregulation contributes to retinal ganglion cell degeneration via JNK3Cell death and differentiationMarch 1, 2018Liu C, Zhang CW, Zhou Y, Wong WQ, Lee LC, Ong WY, Yoon SO, Hong W, Fu XY, Soong TW, et al.Tuj1 (1:400, catalog no. MMS435P, Covance) [56] or sheep antibody against GFAP (1:200, catalog no. AF2594, R&D Systems) was added into the blocking solution and incubated over two nights at 4 °C. After three

(10) Acute doses of caffeine shift nervous system cell expression profiles toward promotion of neuronal projection growthScientific reportsSeptember 13, 2017Yu NY, Bieder A, Raman A, Mileti E, Katayama S, Einarsdottir E, Fredholm BB, Falk A, Tapia-Páez I, Daub CO, et al.antibody (anti-Map2, Abcam, ab5392, 1:500; anti-NeuN, Millipore, ABN78, 1:200; anti-GFAP, R&D systems, AF2594, 1:2000; anti-βIII-tubulin (anti-TUJ1), Covance, MMS-435P, 1:400). Cells were incubated for 1 h at room

(11) Time-Dependent, HIV-Tat-Induced Perturbation of Human Neurons In Vitro: Towards a Model for the Molecular Pathology of HIV-Associated Neurocognitive DisordersFrontiers in molecular neuroscienceJanuary 1, 2017Gurwitz KT, Burman RJ, Murugan BD, Garnett S, Ganief T, Soares NC, Raimondo JV, Blackburn JM.MAB1195, 1:200)—a neuronal marker—and sheep anti-Glial fibrillary acidic protein (GFAP; R&D Systems, AF2594, 1:50)—a glial marker. Wells were then washed three times with PBS followed by a 1-h incubation with

(12) Simultaneous Isolation of Three Different Stem Cell Populations from Murine SkinPloS oneJanuary 1, 2015Forni MF, Ramos Maia Lobba A, Pereira Ferreira AH, Sogayar MC.anti-fibronectin (1:200; R&D Systems, catalog number # AF19181), anti-GFAP (1:400; R&D Systems, catalog number # AF2594), anti-βIII tubulin (1:200; R&D Systems, catalog number # MAB1195), anti-vimentin (1:200; R&D Systems,

(13) Function of mouse embryonic stem cell-derived supporting cells in neural progenitor cell maturation and long term expansionPloS oneJanuary 1, 2013Guan Y, Du QA, Zhu W, Zou C, Wu D, Chen L, Zhang YA.UK). The antibodies included polyclonal goat anti- mouse glial fibrillary acidic protein (GFAP; 1∶600, AF2594; R&D Systems) and monoclonal mouse anti-mouse Tuj-1 (1∶400, MAB1637, Millipore, USA). The secondary

(14) Dose-dependent changes in neuroinflammatory and arachidonic acid cascade markers with synaptic marker loss in rat lipopolysaccharide infusion model of neuroinflammationBMC neuroscienceMay 23, 2012Kellom M, Basselin M, Keleshian VL, Chen M, Rapoport SI, Rao JS.

(15) TNFalpha-induced AMPA-receptor trafficking in CNS neurons; relevance to excitotoxicity?Neuron glia biologyAugust 1, 2004Leonoudakis D, Braithwaite SP, Beattie MS, Beattie EC.

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GFAP Antibody

GFAP Antibody

GFAP Antibody

GFAP Antibody

GFAP Antibody

Human/Rat GFAP Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (15)

Reviews

Human/Rat GFAP Antibody from R&D Systems, a Bio-Techne Brand

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