Supplier Page from Novus Biologicals, a Bio-Techne Brand for Retinol Binding Protein RBP Antibody (G4E4) [DyLight 594]
Available conjugates: Available conjugates: Janelia Fluor 525, DyLight 594, FITC, Biotin, Alexa Fluor 700, Janelia Fluor 669, Alexa Fluor 405, DyLight 488, Alexa Fluor 750, Janelia Fluor 646Specificity: This monoclonal antibody recognizes an epitope within the 74-182 C-terminal sequence (11kD peptide fragment) of human serum Cellular Retinol Binding Protein 1 (CRBP 1), a single-chain glycoprotein belonging to the superfamily of hydrophobic molecule transporter proteins, which is responsible for transport of retinol (vitamin A1) from the liver to peripheral target tissues, like the eye, where it mediates the cellular uptake. CRBP 1 is synthesized by hepatic parenchymal cells where it becomes bound to its ligand retinol and is then released into the circulation, where it binds further to the protein transthyretin, to form a transporting complex, which is big enough not to be lost by filtration through the kidney glomeruli. It is detected in nearly all tissues with higher expression in adult ovary, pancreas, pituitary gland, adrenal gland, and fetal liver.Sizes Available: 0.1 ml