The MAGEC2 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to MAGEC2. This antibody recognizes Human antigen. The MAGEC2 Antibody has been shown to work in the following applications: ELISA, and Western Blot.
Description
Function: Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. In vitro enhances ubiquitin ligase activity of TRIM28 and stimulates p53/TP53 ubiquitination in presence of Ubl-conjugating enzyme UBE2H leading to p53/TP53 degradation. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzymes (E2) at the E3:substrate complex.
Subunit Structure: Interacts with TRIM28 and UBE2H