MyBioSource.com's PCCB Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, Immunohistochemistry, and Western Blot. The PCCB Antibody was generated using PCCB as the antigen and it reacts with Human, Mouse, and Rat.
Description
Description: The protein encoded by this gene is a subunit of the propionyl-CoA carboxylase (PCC) enzyme, which is involved in the catabolism of propionyl-CoA. PCC is a mitochondrial enzyme that probably acts as a dodecamer of six alpha subunits and six beta subunits. This gene encodes the beta subunit of PCC. Defects in this gene are a cause of propionic acidemia type II (PA-2). Multiple transcript variants encoding different isoforms have been found for this gene.
Function: ATP + propanoyl-CoA + HCO3-= ADP + phosphate + (S)-methylmalonyl-CoA.
Subunit Structure: Probably a dodecamer composed of six biotin-containing alpha subunits and six beta subunits.
Similarity: Belongs to the AccD/PCCB family