The CEP72 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to CEP72. This antibody recognizes Human, and Mouse antigen. The CEP72 Antibody has been shown to work in the following applications: ELISA, Immunohistochemistry, and Western Blot.
Description
Function: Involved in the recruitment of key centrosomal proteins to the centrosome. Provides centrosomal microtubule-nucleation activity on the gamma-tubulin ring complexes (gamma-TuRCs) and has critical roles in forming a focused bipolar spindle, which is needed for proper tension generation between sister chromatids. Required for localization of KIZ, AKAP9 and gamma-tubulin ring complexes (gamma-TuRCs) (PubMed:19536135). Involved in centriole duplication. Required for CDK5RAP22, CEP152, WDR62 and CEP63 centrosomal localization and promotes the centrosomal localization of CDK2 (PubMed:26297806).
Subunit Structure: Interacts with KIZ, PCM1 and CDK5RAP2.
Similarity: Belongs to the CEP72 family