The ERLIN1 Mouse mAb Antibody from MyBioSource.com is a Mouse Monoclonal antibody. This antibody recognizes Human antigen. The ERLIN1 Mouse mAb Antibody has been shown to work in the following applications: Flow Cytometry, Immunoprecipitation, and Western Blot.
Description
Component of the ERLIN1, ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1, 4, 5-trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. Binds cholesterol and may promote ER retention of the SCAP-SREBF complex