The WASF3 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to WASF3. This antibody recognizes Human, and Mouse antigen. The WASF3 Antibody has been shown to work in the following applications: ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
Function: Downstream effector molecules involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape.
Subunit Structure: Binds actin and the Arp2/3 complex.
Post-translational Modifications: Phosphorylation by ABL1 promotes lamellipodia formation and cell migration.
Similarity: Binds the Arp2/3 complex through the C-terminal region and actin through verprolin homology (VPH) domain. Belongs to the SCAR/WAVE family