The BCAS3 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to BCAS3. This antibody recognizes Human, and Mouse antigen. The BCAS3 Antibody has been shown to work in the following applications: ELISA, Immunocytochemistry, Immunofluorescence, and Western Blot.
Description
Function: Plays a role in angiogenesis. Participates in the regulation of cell polarity and directional endothelial cell migration by mediating both the activation and recruitment of CDC42 and the reorganization of the actin cytoskeleton at the cell leading edge. Promotes filipodia formation (By similarity). Functions synergistically with PELP1 as a transcriptional coactivator of estrogen receptor-responsive genes. Stimulates histone acetyltransferase activity. Binds to chromatin.
Subunit Structure: Interacts with histone H3, ESR1, KAT2B and PELP1; the interactions occur in a estrogen-dependent manner. Interacts with beta-tubulin and VIM.
Similarity: Has been proposed to contain 7 WD repeats. This prediction could not be reproduced. Belongs to the BCAS3 family