Fig 2: a Presence of collagen-associated autoantibodies. Col III = collagen type III, Col IV = collagen type IV, MMP-9 = matrix metalloproteinase-9, TIMP-1 = tissue inhibitors of metalloproteinases-1, TNC = tenascin-C, CC = collagenous colitis. Relative units > 97.5 percentile in a cohort of healthy blood donors were considered as presence of antibodies. Controls consisted of a = 70, ß = 51, ? = 100, d = 65 healthy blood donors. Fischer's exact test was used to calculate the differences between groups. None of the differences between groups were statistically significant (P < 0.05). b Presence of antibodies against saccharomyces cerevisiae (ASCA), thyroid peroxidase (TPO) and increased total serum IgE. CC = Collagenous colitis. Controls consisted of a = 50 healthy blood donors, ß = 254 healthy blood donors, ? = 100 healthy blood donors. Fischer's exact test was used to calculate the differences between groups. None of the differences between groups were statistically significant (P < 0.05)