The HSP60 polyclonal antibody from MyBioSource.com is a Goat Polyclonal antibody to HSPD1. This antibody recognizes Human, Mouse, Rat, Bacteria/Archaea, Bovine, Canine, Chicken/Bird, Drosophila/Arthropod, Guinea Pig, Hamster, Non-Human Primate, Porcine, Rabbit, Sheep, Xenopus/Amphibian, Zebrafish/Fish, and Other Mammalian antigen. The HSP60 polyclonal antibody has been shown to work in the following applications: Immunohistochemistry, Immunoprecipitation, and Western Blot.
Description
Hsp60 is a member of the chaperonin family of heat shock proteins, with homologs functioning in the cytosol and mitochondria to fold nascent and aggregated proteins. Hsp60 is the eukaryotic homolog of the E Coli GroEL protein, and forms a multimeric complex in the mitochondria with Hsp10 (Cpn10) to form a large central cavity in which ATP-dependent protein folding takes place. TRiC/CCT, a eukaryotic relative of Hsp60, is expressed in the cytosol and participates in the folding of actin and tubulin substrates, but lacks any association with an Hsp10-like co-factor