Human IL-18 Rß/IL-1 R7 Antibody MAB1181 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemHuman IL-18 Rß/IL-1 R7 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $589.00Supplier Page View Company Product Page
Catalog NumberMAB1181
Quantity500 ug (also 25 ug)
ApplicationsFlow Cytometry,Western Blot,Neutralization
Conjugate/TagUnconjugated
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ConcentrationLYOPH
PurityProtein A or G purified from hybridoma culture supernatant
IsotypeIgG1
HostMouse
Clone132016
TargetIL-18 R beta/IL-1 R7
ReactivityHuman
Antibody TypePrimary Antibodies
NCBI Gene AliasesIL-18RAcP, IL-1RAcPL, IL-1R-7, IL-18R-beta, IL-1R7, IL-18Rbeta, CDw218b, CD218b, ACPL, IL18RB
NCBI Full Gene Nameinterleukin 18 receptor accessory protein
ClonalityMonoclonal
ImmunogenMouse myeloma cell line NS0-derived recombinant human IL-18 Rß/IL-1 R7, Met1-Arg356, Accession # O95256
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Unconjugated

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) A novel anti-human IL-1R7 antibody reduces IL-18-mediated inflammatory signalingThe Journal of biological chemistryJanuary 1, 2021Li S, Jiang L, Beckmann K, Højen JF, Pessara U, Powers NE, de Graaf DM, Azam T, Lindenberger J, Eisenmesser EZ, et al.IL-37 46-218 was produced as described earlier (97). The reference anti-IL-1R7 monoclonal antibody MAB1181 of R&D Systems (R&D MAB1181 Reference mAB) and the anti-IL-37 monoclonal antibody were from Bio-Techne.

(2) The IL18RAP region disease polymorphism decreases IL-18RAP/IL-18R1/IL-1R1 expression and signaling through innate receptor-initiated pathwaysJournal of immunology (Baltimore, Md. : 1950)June 15, 2014Hedl M, Zheng S, Abraham C.

(3) Soluble interleukin-18 receptor complex is a novel biomarker in rheumatoid arthritisArthritis research & therapyMarch 24, 2011Takei S, Hoshino T, Matsunaga K, Sakazaki Y, Sawada M, Oda H, Takenaka S, Imaoka H, Kinoshita T, Honda S, et al.(mAb) (clone 70625; catalog no. MAB840) and mouse antihuman IL-18Rβ mAb (clone 132016, catalog no. MAB1181; and clone 132029, catalog no. MAB118) were purchased from R&D Systems, Inc. (Minneapolis, MN, USA).

(4) CD molecules 2006--human cell differentiation moleculesJournal of immunological methodsJanuary 30, 2007Zola H, Swart B, Banham A, Barry S, Beare A, Bensussan A, Boumsell L, D Buckley C, Bühring HJ, Clark G, et al.

(5) IL-18 receptor beta-induced changes in the presentation of IL-18 binding sites affect ligand binding and signal transductionJournal of immunology (Baltimore, Md. : 1950)June 1, 2003Wu C, Sakorafas P, Miller R, McCarthy D, Scesney S, Dixon R, Ghayur T.

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IL-18 R beta/IL-1 R7 Antibody

IL-18 R beta/IL-1 R7 Antibody

Human IL-18 Rß/IL-1 R7 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (5)

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Human IL-18 Rß/IL-1 R7 Antibody from R&D Systems, a Bio-Techne Brand

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