MCAM/CD146 Antibody AF932 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemMCAM/CD146 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $519.00Supplier Page View Company Product Page
Catalog NumberAF932
ApplicationsImmunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Simple Western,Immunocytochemistry
IsotypeIgG
HostGoat
TargetMCAM/CD146
Conjugate/TagUnconjugated
Quantity100 ug (also 25 ug)
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ReactivityHuman,Mouse
ClonalityPolyclonal
ImmunogenMouse myeloma cell line NS0-derived recombinant human MCAM/CD146, Met1-Gly559, Accession # AAA20824
ConcentrationLYOPH
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution
NCBI Full Gene Namemelanoma cell adhesion molecule
NCBI Gene AliasesCD146, HEMCAM, METCAM, MUC18, MelCAM

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects human MCAM/CD46 in Western blots and direct ELISAs. In direct ELISAs, less than 10% cross-reactivity with recombinant human (rh) ALCAM, rhBCAM, rhNCAM-L1, rhTROP-2 and recombinant mouse MCAM is observed.

Sizes Available: 100 ug (also 25 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Immunoregulatory Roles of Tumor‐Originated Pericytes Identified by Single‐Cell Analysis in GlioblastomaAdvanced ScienceSeptember 26, 2025Cuiying Chu, Fangzhen Li, Zhiwen Zhang, Qiuhong Zhu, Hong Yan, Mengdan Cheng, Huipeng Wang, Lei Cheng, Zhe Zhang, Xingjiang Yu, et al.staining was subjected to microscopy. Specific antibodies against CD146 (Abcam, ab75769; R&D Systems, AF932), CD31 (Dako, M082301), PDGFRβ (Cell Signaling Technology, 3169S), Desmin (Proteintech, 16520‐1‐AP),

(2) Mitochondrial ROS drive foam cell formation via STAT5 signaling in atherosclerosisScience advancesAugust 29, 2025Boccuni L, Marka F, Salzmann M, Schirripa A, Ableitner E, Siller M, Brekalo M, Haider P, Stojkovic S, Neumayer C, et al.

(3) Cranioencephalic functional lymphoid units in glioblastomaNature medicineOctober 1, 2024Dobersalske C, Rauschenbach L, Hua Y, Berliner C, Steinbach A, Grüneboom A, Kokkaliaris KD, Heiland DH, Berger P, Langer S, et al.

(4) Cancer-associated fibroblast phenotypes are associated with patient outcome in non-small cell lung cancerCancer cellMarch 11, 2024Cords L, Engler S, Haberecker M, Rüschoff JH, Moch H, de Souza N, Bodenmiller B.AB_2894842 Goat polyclonal anti-CD146; Clone (Polyclonal_MCAM/CD146_RnD_AF932); Lot(ECL0319041),R&D Systems,Cat#AF932; RRID: AB_355721 Mouse monoclonal anti-SMA; Clone (1A4); Lot(2183900),eBioscience,Cat#14-9760-82; RRID:

(5) Characterization of novel neutralizing mouse monoclonal antibody JM1-24-3 developed against MUC18 in metastatic melanomaJournal of experimental & clinical cancer research : CRDecember 5, 2020Feng R, Wang Y, Ramachandran V, Ma Q, May MM, Li M, Zhou JX, Xu X, Xu K, Fang S, et al.antibodies used in this study include anti-human MUC18 (mouse mAb, Cat. #MAB932; goat polyclonal Ab, Cat. #AF932, R&D Systems, Inc., Minneapolis, MN; mouse mAb, Cat # ab233923; AbCam, Cambridge, MA) and an irrelevant

(6) Single-Cell Analysis of Human Ovarian Cortex Identifies Distinct Cell Populations But No Oogonial Stem CellsObstetrical & Gynecological SurveyJune 1, 2020Magdalena Wagner et al.antibodies (DDX4, ab13840, Abcam; DDX4, SAB1300533, Sigma-Aldrich; DDX4, AP1403b, Abgent; MCAM (1:100), AF932, R&D Systems; CD9 (1:20), ab2215, Abcam) diluted in blocking solution. DDX4 antibody was titrated using concentrations

(7) Single-cell analysis of human ovarian cortex identifies distinct cell populations but no oogonial stem cellsNature communicationsMarch 2, 2020Wagner M, Yoshihara M, Douagi I, Damdimopoulos A, Panula S, Petropoulos S, Lu H, Pettersson K, Palm K, Katayama S, et al.antibodies (DDX4, ab13840, Abcam; DDX4, SAB1300533, Sigma-Aldrich; DDX4, AP1403b, Abgent; MCAM (1:100), AF932, R&D Systems; CD9 (1:20), ab2215, Abcam) diluted in blocking solution. DDX4 antibody was titrated using

(8) Platelet-Derived Growth Factor Receptor-Positive Pericytic Cells of White Adipose Tissue from Critical Limb Ischemia Patients Display Mesenchymal Stem Cell-Like PropertiesClinics in orthopedic surgeryJune 1, 2017Kim EJ, Seo SG, Shin HS, Lee DJ, Kim JH, Lee DY.

(9) Chemotherapy enhances tumor vascularization via Notch signaling-mediated formation of tumor-derived endothelium in breast cancerBiochemical pharmacologyOctober 15, 2016Zhang P, He D, Chen Z, Pan Q, Du F, Zang X, Wang Y, Tang C, Li H, Lu H, et al.

(10) CD105 expression on CD34-negative spindle-shaped stromal cells of primary tumor is an unfavorable prognostic marker in early breast cancer patientsPloS oneJanuary 1, 2015Martinez LM, Labovsky V, Calcagno ML, Davies KM, Garcia Rivello H, Bianchi MS, Wernicke A, Fernández Vallone VB, Chasseing NA.R&D Systems), FSP (mouse IgM; F4771; Sigma-Aldrich), CD105 (goat IgG; AF1097; R&D Systems) or CD146 (goat IgG; AF932; R&D Systems) overnight at 4°C in a humid environment. Next, LSAB+ System-HRP (K0690; Dako) and 3-3´-diaminobenzidine

(11) Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglionPloS oneJanuary 1, 2015Gu Z, Imai F, Kim IJ, Fujita H, Katayama Ki, Mori K, Yoshihara Y, Yoshida Y.

(12) Endothelial endoglin is involved in inflammation: role in leukocyte adhesion and transmigrationBloodJanuary 10, 2013Rossi E, Sanz-Rodriguez F, Eleno N, Düwell A, Blanco FJ, Langa C, Botella LM, Cabañas C, Lopez-Novoa JM, Bernabeu C.

(13) Plasticity of blood- and lymphatic endothelial cells and marker identificationPloS oneJanuary 1, 2013Keuschnigg J, Karinen S, Auvinen K, Irjala H, Mpindi JP, Kallioniemi O, Hautaniemi S, Jalkanen S, Salmi M.

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MCAM/CD146 Antibody

MCAM/CD146 Antibody

MCAM/CD146 Antibody

MCAM/CD146 Antibody

MCAM/CD146 Antibody

MCAM/CD146 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (13)

Reviews

MCAM/CD146 Antibody from R&D Systems, a Bio-Techne Brand

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