Mouse IL-17RA/IL-17R Antibody AF448 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemMouse IL-17RA/IL-17R Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $479.00Supplier Page View Company Product Page
Catalog NumberAF448
ApplicationsFlow Cytometry,Immunoprecipitation,Western Blot,Neutralization,Immunocytochemistry,CyTOF-ready
Conjugate/TagUnconjugated
Quantity100 ug (also 25 ug)
ReactivityMouse
TargetIL-17RA/IL-17R
IsotypeIgG
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
HostGoat
ClonalityPolyclonal
ImmunogenS. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse IL-17 RA/IL-17 R, Extracellular domain
ConcentrationLYOPH
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution
NCBI Full Gene Nameinterleukin 17 receptor A
NCBI Gene AliasesCdw217, Il17r, VDw217

Specifications/Features

Available conjugates: Unconjugated

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) T cells regulate intestinal motility and shape enteric neuronal responses to intestinal microbiotaGut MicrobesDecember 31, 2025Patricia Rodrigues Marques de Souza, Catherine M. Keenan, Laurie E. Wallace, Yasaman Bahojb Habibyan, Marcela Davoli-Ferreira, Christina Ohland, Fernando A. Vicentini, Kathy D. McCoy, Keith A. SharkeyAB_355110 Mouse anti-Nestin,1:100,Abcam,Cat# ab6142; RRID: AB_305313 Goat anti-IL17R,1:100,R&D Systems,Cat# AF448; RRID: AB_355366 Sheep anti-nNOS,1:200,Millipore Sigma,Cat# AB1529; RRID: AB_90743 Donkey anti-mouse

(2) Population snapshots predict early haematopoietic and erythroid hierarchiesNatureMarch 1, 2018Tusi BK, Wolock SL, Weinreb C, Hwang Y, Hidalgo D, Zilionis R, Waisman A, Huh JR, Klein AM, Socolovsky M.(Bethyl Laboratories, Inc., A300-191A), PCNA (PC10) (Santa Cruz, sc-56), IL-17RA/IL-17R (R&D Systems, AF448). Western blot membranes were quantified using the BIORAD Imaging system and Image Lab software. Intracellular

(3) Anti-CD3 antibody therapy attenuates the progression of hypertension in female mice with systemic lupus erythematosusPharmacological researchJune 1, 2017Mathis KW, Taylor EB, Ryan MJ.of the interleukin 17 receptor (IL-17RA) was assessed using a polyclonal goat anti mouse antibody (AF448, R&D Systems). Pharmacol Res. Author manuscript; available in PMC 2018 June 01. Mathis et al. Page

(4) IL-17 Augments B Cell Activation in Ocular Surface AutoimmunityJournal of immunology (Baltimore, Md. : 1950)November 1, 2016Subbarayal B, Chauhan SK, Di Zazzo A, Dana R.

(5) IL-17RA is essential for optimal localization of follicular Th cells in the germinal center light zone to promote autoantibody-producing B cellsJournal of immunology (Baltimore, Md. : 1950)August 15, 2013Ding Y, Li J, Wu Q, Yang P, Luo B, Xie S, Druey KM, Zajac AJ, Hsu HC, Mountz JD.and Alexa 555–goat-anti-rat IgG (A21434); goat anti-mouse IL-21 (AF594, R&D Systems) and anti-IL-17R (AF448, R&D Systems) followed by Alexa 647-donkey-anti-goat IgG. Application of chicken anti-mouse RGS16 (NB300-350,

(6) IFN-alpha enhances peptide vaccine-induced CD8+ T cell numbers, effector function, and antitumor activityJournal of immunology (Baltimore, Md. : 1950)June 15, 2009Sikora AG, Jaffarzad N, Hailemichael Y, Gelbard A, Stonier SW, Schluns KS, Frasca L, Lou Y, Liu C, Andersson HA, et al.

(7) A protective function for interleukin 17A in T cell-mediated intestinal inflammationNature immunologyJune 1, 2009O'Connor W Jr, Kamanaka M, Booth CJ, Town T, Nakae S, Iwakura Y, Kolls JK, Flavell RA.manufacturer's instructions. Secondary antibodies were from Santa Cruz. Polyclonal anti-mouse IL-17R (AF448; R&D Systems) was used in immunoprecipitation experiments. T cells were lysed in 1% (vol/vol) NonidetP40

(8) TLR2 deficiency leads to increased Th17 infiltrates in experimental brain abscessesJournal of immunology (Baltimore, Md. : 1950)June 1, 2009Nichols JR, Aldrich AL, Mariani MM, Vidlak D, Esen N, Kielian T.

(9) Functional interleukin-17 receptor A is expressed in central nervous system glia and upregulated in experimental autoimmune encephalomyelitisJournal of neuroinflammationApril 28, 2009Das Sarma J, Ciric B, Marek R, Sadhukhan S, Caruso ML, Shafagh J, Fitzgerald DC, Shindler KS, Rostami A.

(10) IL-17RD (Sef or IL-17RLM) interacts with IL-17 receptor and mediates IL-17 signalingCell researchFebruary 1, 2009Rong Z, Wang A, Li Z, Ren Y, Cheng L, Li Y, Wang Y, Ren F, Zhang X, Hu J, et al.

(11) IL-17 receptor signaling influences virus-induced corneal inflammationJournal of leukocyte biologyFebruary 1, 2008Molesworth-Kenyon SJ, Yin R, Oakes JE, Lausch RN.

(12) Interleukin 17–producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 miceNature ImmunologyFebruary 1, 2008Hui-Chen Hsu et al.(RM4-5, Invitrogen) to Alexa 488 or Alexa 647; anti–IL-17 (50101, R&D Systems) to Alexa 555; and anti–IL-17R (AF448, R&D Systems) to Alexa 488. Sections were mounted in Fluormount G (Southern Biotechnology) and viewed

(13) Inhibition of interleukin-17 prevents the development of arthritis in vaccinated mice challenged with Borrelia burgdorferiInfection and immunityJune 1, 2003Burchill MA, Nardelli DT, England DM, DeCoster DJ, Christopherson JA, Callister SM, Schell RF.

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IL-17RA/IL-17R Antibody

IL-17RA/IL-17R Antibody

IL-17RA/IL-17R Antibody

IL-17RA/IL-17R Antibody

IL-17RA/IL-17R Antibody

Mouse IL-17RA/IL-17R Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (13)

Reviews

Mouse IL-17RA/IL-17R Antibody from R&D Systems, a Bio-Techne Brand

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