Mouse TRAIL R2/TNFRSF10B Antibody AF721 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemMouse TRAIL R2/TNFRSF10B Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $489.00Supplier Page View Company Product Page
Catalog NumberAF721
ApplicationsFlow Cytometry,Western Blot,Neutralization,CyTOF-ready
ReactivityHuman,Mouse
TargetTRAIL R2/TNFRSF10B
HostGoat
Quantity100 ug (also 25 ug)
Conjugate/TagUnconjugated
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
IsotypeIgG
ClonalityPolyclonal
ImmunogenMouse myeloma cell line NS0-derived recombinant mouse TRAIL R2/TNFRSF10B, Asn53-Ser177, Accession # Q6GSD9
ConcentrationLYOPH
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution
NCBI Full Gene Nametumor necrosis factor receptor superfamily, member 10b
NCBI Gene AliasesDR5, KILLER, Ly98, MK, TRAILR2, TRICK2A, TRICK2B, TRICKB

Specifications/Features

Available conjugates: Unconjugated

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Lymph node and tumor-associated PD-L1(+) macrophages antagonize dendritic cell vaccines by suppressing CD8(+) T cellsCell reports. MedicineJanuary 16, 2024Sprooten J, Vanmeerbeek I, Datsi A, Govaerts J, Naulaerts S, Laureano RS, Borràs DM, Calvet A, Malviya V, Kuballa M, et al.RRID:AB_326523 anti-mouse TNF,Invitrogen,Cat#16-7423-81 RRID:AB_469261 anti-mouse TRAIL,R&D systems,Cat#AF721 RRID:AB_2205069 anti-mouse PDL1 D265A mutated,invivogen,Cat#pdl1-mab15 anti-mouse CSF1R (clone: AFS98),BioXCell,Cat#BP0213

(2) A Dual Role for Death Receptor 5 in Regulating Cardiac Fibroblast FunctionFrontiers in cardiovascular medicineJanuary 1, 2021Tanner MA, Grisanti LA.9101), total-ERK1/2 (1:1,000; Cell Signaling, catalog # 4696), DR5 (1:1,000; R&D Systems, catalog # AF721), or GAPDH (1:1,000; Cell Signaling, catalog # 2118). After washing, membranes were incubated with the

(3) Muscle-derived TRAIL negatively regulates myogenic differentiationExperimental cell researchSeptember 1, 2020Kim D, Singh N, Waldemer-Streyer RJ, Yoon MS, Chen J.(ab11304, 1:10000) and anti-p21 (ab109199, 1:500) were from Abcam (Cambridge, MA, USA). Anti-TRAIL-R2 (AF721, 1:1000) and human TRAIL recombinant protein (375-TEC) were from R&D Systems (Minneapolis, MN, USA).

(4) Death receptor 5 contributes to cardiomyocyte hypertrophy through epidermal growth factor receptor transactivationJournal of Molecular and Cellular CardiologyNovember 1, 2019Miles A. Tanner, Toby P. Thomas, Laurel A. Grisantifraction. Immunoblotting was performed with diluted antibodies against DR5 (1:2000; R&D Systems, catalog # AF721), GATA4 (1:1000; eBioscience, catalog # 50–139–53), GAPDH (1:1000; Cell Signaling, catalog #2118), Na+/K

(5) IAP antagonists sensitize murine osteosarcoma cells to killing by TNFαOncotargetJune 7, 2016Shekhar TM, Miles MA, Gupte A, Taylor S, Tascone B, Walkley CR, Hawkins CJ.

(6) Bortezomib treatment and regulatory T-cell depletion enhance the antitumor effects of adoptively infused NK cellsBloodJune 11, 2009Lundqvist A, Yokoyama H, Smith A, Berg M, Childs R.

(7) P-glycoprotein enhances TRAIL-triggered apoptosis in multidrug resistant cancer cells by interacting with the death receptor DR5Biochemical pharmacologyJuly 28, 2006Park SJ, Wu CH, Choi MR, Najafi F, Emami A, Safa AR.

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TRAIL R2/TNFRSF10B Antibody

TRAIL R2/TNFRSF10B Antibody

Mouse TRAIL R2/TNFRSF10B Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (7)

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Mouse TRAIL R2/TNFRSF10B Antibody from R&D Systems, a Bio-Techne Brand

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