Human Activin RIIB Antibody AF339 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemHuman Activin RIIB Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $539.00Supplier Page View Company Product Page
Catalog NumberAF339
Quantity100 ug (also 25 ug)
ApplicationsImmunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Blockade of Receptor-ligand Interaction,Cell Culture
Conjugate/TagUnconjugated
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ConcentrationLYOPH
PurityAntigen Affinity-purified
TargetActivin RIIB
HostGoat
ReactivityFeline,Human,Mouse,Ovine,Rat
IsotypeIgG
Antibody TypePrimary Antibodies
ClonalityPolyclonal
ImmunogenMouse myeloma cell line NS0-derived recombinant human Activin RIIB, Ser19-Thr134, Accession # CAA54671
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution
NCBI Full Gene Nameactivin A receptor type 2B
NCBI Gene AliasesACTRIIB, ActR-IIB, HTX4

Specifications/Features

Available conjugates: Unconjugated

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Periodontitis induces skeletal muscle atrophy by increasing circulating levels of activin ANat CommunMay 6, 2026Wonn Shim, Joonho Suh, Ha Kyeong Kim, Na-Kyung Kim, Yongbaek Kim, Yong Taek Jeong, Min-Sung Kim, Se-Jin Lee, Yun-Sil Leeanti-FLAG together with anti-ACVR2A (1:15, R&D Systems, AF340) and anti-ACVR2B (1:15, R&D Systems, AF339) antibodies, followed by goat anti-rabbit Alexa 594 secondary antibody (1:500, Invitrogen, A-11012)

(2) Combined detection of inhibitors of the activin receptor signaling pathways (IASPs) by means of LC-HRMS/MS for human doping controlSci RepJune 6, 2025Panagiotis Sakellariou, Katja Walpurgis, Andreas Thomas, Alexandre Marchand, Geoff Miller, Frank Dellanna, Mario Thevis(Munich, Germany), latent MSTN from Kactus (Paris, France) and a goat anti-human ActRIIB antibody (AF339) from R&D Systems (Minnesota, USA). Reagents required for protein reduction and alkylation were tris(2-carboxyethyl)phosphine

(3) Potential roles of activin in head and neck squamous cell carcinoma progression in epithelial-mesenchymal transition, metastasis, and mortalityAnticancer ResearchJuly 20, 2024SETH BURYSKA, KETAN PATEL, BEVERLY WUERTZ, PATRICK M. GAFFNEY, FRANK ONDREYAntibody,Clone,Source,Dilution ACVR1B (MAB222),Monoclonal,R & D Systems,1:200 ACVR2 (AF340),Polyclonal,R & D Systems,1:100 ACVR2B (AF339),Polyclonal,R & D Systems,1:80 INHA (MCA951S),Monoclonal,Biorad,1:800 INHBA (Serotec/Biorad),Monoclonal,Biorad,1:100 INHBB

(4) Circulating activin A during equine gestation and immunolocalization of its receptors system in utero-placental tissues and fetal gonadsJournal of equine scienceJune 1, 2021Dhakal P, Tsunoda N, Nambo Y, Taniyama H, Nagaoka K, Watanabe G, Taya K.3-aminopropyltriethoxysilane. Goat polyclonal antibodies against activin receptors IA (AF637) and IIB (AF339) were purchased from R&D Systems (Minneapolis, MN, U.S.A.). Goat polyclonal antibody against activin

(5) Activin receptors regulate the oligodendrocyte lineage in health and diseaseActa neuropathologicaJune 1, 2018Dillenburg A, Ireland G, Holloway RK, Davies CL, Evans FL, Swire M, Bechler ME, Soong D, Yuen TJ, Su GH, et al.with activin-A and neutralizing antibodies against Acvr2a or Acvr2b (30 μg ml−1, R&D Systems; AF340, AF339) or goat IgG isotype control (30 μg ml−1, Santa Cruz Biotechnology). Cells were matured to oligodendrocytes

(6) Downregulated Translation Initiation Signaling Predisposes Low-Birth-Weight Neonatal Pigs to Slower Rates of Muscle Protein SynthesisFrontiers in physiologyJanuary 1, 2017Chen Y, McCauley SR, Johnson SE, Rhoads RP, El-Kadi SW.antibodies used for western blot. Antibody Company ALK5 #AF3025; R&D systems, Minneapolis, MN ActRIIB #AF339; R&D systems, Minneapolis, MN 4EBP1 #A300-501A; Bethyl Laboratories, Montgomery, TX eIF3e #AB1114851;

(7) M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelinationNature neuroscienceSeptember 1, 2013Miron VE, Boyd A, Zhao JW, Yuen TJ, Ruckh JM, Shadrach JL, van Wijngaarden P, Wagers AJ, Williams A, Franklin RJM, et al.receptors include goat anti-activin-A (AF338), anti-Acvr1B (AF1477), anti-Acvr2A (AF340), and anti-Acvr2B (AF339) (all from R & D Systems, 1:40). Other antibodies include chicken anti-NFH (Encor Biotechnology, Inc.,

(8) Activin acutely sensitizes dorsal root ganglion neurons and induces hyperalgesia via PKC-mediated potentiation of transient receptor potential vanilloid IThe Journal of neuroscience : the official journal of the Society for NeuroscienceDecember 12, 2007Zhu W, Xu P, Cuascut FX, Hall AK, Oxford GS.receptors were also purchased from R&D Systems (RIA catalog #AF637; RIB catalog # AF222; RIIB catalog #AF339; RIIA catalog #AF340). PKC␧ polyclonal antibody was purchased from Assay Designs (Ann Arbor, MI). Rat TRPV1

(9) Postnatal regulation of germ cells by activin: the establishment of the initial follicle poolDevelopmental biologyOctober 1, 2006Bristol-Gould SK, Kreeger PK, Selkirk CG, Kilen SM, Cook RW, Kipp JL, Shea LD, Mayo KE, Woodruff TK.

(10) Activin A is an endogenous inhibitor of ureteric bud outgrowth from the Wolffian ductDevelopmental biologyJuly 15, 2006Maeshima A, Vaughn DA, Choi Y, Nigam SK.

(11) Activin and inhibin receptor gene expression in the ewe pituitary throughout the oestrous cycleThe Journal of endocrinologyJuly 1, 2004Fafioffe A, Ethier JF, Fontaine J, JeanPierre E, Taragnat C, Dupont J.

(12) Follicle-restricted compartmentalization of transforming growth factor beta superfamily ligands in the feline ovaryBiology of reproductionMarch 1, 2004Bristol SK, Woodruff TK.

(13) Regulation of endocytosis of activin type II receptors by a novel PDZ protein through Ral/Ral-binding protein 1-dependent pathwayThe Journal of biological chemistryMay 24, 2002Matsuzaki T, Hanai S, Kishi H, Liu Z, Bao Y, Kikuchi A, Tsuchida K, Sugino H.