MMP-3 Antibody AF513 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemMMP-3 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $499.00Supplier Page View Company Product Page
Catalog NumberAF513
NCBI Gene AliasesCHDS6, MMP-3, STMY1, STR1, STMY, SL-1
Quantity100 ug (also 25 ug)
ReactivityHuman,Mouse,Primate
TargetMMP-3
Conjugate/TagUnconjugated
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
IsotypeIgG
HostGoat
NCBI Full Gene Namematrix metallopeptidase 3
ApplicationsWB, ELISA, ELISA-cap, IHC, IHC-fr, IHC-p, IP
ClonalityPolyclonal
ImmunogenMouse myeloma cell line NS0-derived recombinant human MMP-3, Tyr18-Cys477 (Lys45Glu), Accession # P08254
ConcentrationLYOPH
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects human and primate MMP-3 in ELISAs and Western blots. In Direct ELISA's, less than 10% cross-reactivity with recombinant human (rh) MMP-10 is observed and less than 1% cross-reactivity with rhMMP-1, -2, -7, -8, -9, -12, -13, and recombinant mouse MMP-9 is observed.

Sizes Available: 100 ug (also 25 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Combination of plasma MMPs and PD-1-binding soluble PD-L1 predicts recurrence in gastric cancer and the efficacy of immune checkpoint inhibitors in non-small cell lung cancerFrontiers in PharmacologyMay 7, 2024Fumihiko Ando, Takeru Kashiwada, Shoko Kuroda, Takenori Fujii, Ryotaro Takano, Yoshishige Miyabe, Shinobu Kunugi, Takashi Sakatani, Akihiko Miyanaga, Tomoko Asatsuma-Okumura, et al.cells, sections were incubated with anti-MMP3, anti-MMP9, and anti-MMP-13 antibodies (R&D systems, #AF513, #MAB911, and #MAB511, respectively). The sections were treated with Histofine Simple Stain MAX-PO (Rabbit),

(2) Endosulfan promotes cell proliferation and extracellular matrix accumulation through TGF-β/Smad signaling pathway in HRMCsEcotoxicology and environmental safetyNovember 30, 2021Liu S, Hu Y, Wang Y, Sun Y, Qin SL, Xu D.

(3) Relevance of Plasma Matrix Metalloproteinase-9 for Bronchiolitis Obliterans Syndrome after Allogeneic Hematopoietic Cell TransplantationTransplant Cell TherSeptember 1, 2021Inamoto Y, Martin PJ, Onstad LE, Cheng GS, Williams KM, Pusic I, Ho VT, Arora M, Pidala J, Flowers MED, et al.following antibodies were used for analysis: MMP-9 #MAB936 (capture) and #BAF911 (detection), MMP-3 #AF513 (capture) and #BAF513 (detection), and YKL-40 #MAB25991 (capture) and #BAF2559 (detection). The lower

(4) NFAT5 Controls the Integrity of EpidermisFrontiers in immunologyJanuary 1, 2021Muhammad K, Xavier D, Klein-Hessling S, Azeem M, Rauschenberger T, Murti K, Avots A, Goebeler M, Klein M, Bopp T, et al.the skin of a human fetus. Sections were stained with Abs against NFAT5 (ab110995, Abcam) and Mmp3 (AF513, Novus Biologicals) and counterstained with DAPI as indicated. Length of the bars: 100 μm.

(5) Targetable mechanisms driving immunoevasion of persistent senescent cells link chemotherapy-resistant cancer to agingJCI insightJune 11, 2019Muñoz DP, Yannone SM, Daemen A, Sun Y, Vakar-Lopez F, Kawahara M, Freund AM, Rodier F, Wu JD, Desprez PY, et al.(Abcam, ab175380), MMP1 (R&D Systems, AF901; Oncogene Research Products, IM35L), MMP3 (R&D Systems, AF513; Oncogene Research Products, IM70T; BioVision, 3523-100), MMP10 (R&D Systems, AF910; Oncogene Research

(6) IL-3 Decreases Cartilage Degeneration by Downregulating Matrix Metalloproteinases and Reduces Joint Destruction in Osteoarthritic MiceJournal of immunology (Baltimore, Md. : 1950)June 15, 2016Kour S, Garimella MG, Shiroor DA, Mhaske ST, Joshi SR, Singh K, Pal S, Mittal M, Krishnan HB, Chattopadhyay N, et al.

(7) Redundancy of IL-1 Isoform Signaling and Its Implications for Arterial RemodelingPloS oneJanuary 1, 2016Beltrami-Moreira M, Vromman A, Sukhova GK, Folco EJ, Libby P.appropriate serum overnight at 4°C. The following primary antibodies were used: goat anti-human MMP-3 (1:20, AF513, R&D Systems), mouse anti-human IL-1α (1:50, MAB200, R&D Systems), rabbit anti-human IL-1β (1:60, sc-7884,

(8) Pre-analytical effects of blood sampling and handling in quantitative immunoassays for rheumatoid arthritisJournal of immunological methodsApril 30, 2012Zhao X, Qureshi F, Eastman PS, Manning WC, Alexander C, Robinson WH, Hesterberg LK.

(9) Guggulsterone blocks IL-1beta-mediated inflammatory responses by suppressing NF-kappaB activation in fibroblast-like synoviocytesLife sciencesJune 6, 2008Lee YR, Lee JH, Noh EM, Kim EK, Song MY, Jung WS, Park SJ, Kim JS, Park JW, Kwon KB, et al.

(10) Advanced glycation end products increases matrix metalloproteinase-1, -3, and -13, and TNF-alpha in human osteoarthritic chondrocytesFEBS lettersMay 1, 2007Nah SS, Choi IY, Yoo B, Kim YG, Moon HB, Lee CK.

(11) Molecular profiling of cervical cancer progressionBritish journal of cancerJanuary 29, 2007Hagemann T, Bozanovic T, Hooper S, Ljubic A, Slettenaar VI, Wilson JL, Singh N, Gayther SA, Shepherd JH, Van Trappen PO.

(12) The role of matrix metalloproteinase-7 in redefining the gastric microenvironment in response to Helicobacter pyloriGastroenterologyMay 1, 2006McCaig C, Duval C, Hemers E, Steele I, Pritchard DM, Przemeck S, Dimaline R, Ahmed S, Bodger K, Kerrigan DD, et al.

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MMP-3 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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MMP-3 Antibody from R&D Systems, a Bio-Techne Brand

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