TGF-beta RI/ALK-5 Antibody AF587 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemTGF-beta RI/ALK-5 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $479.00Supplier Page View Company Product Page
Catalog NumberAF587
ApplicationsImmunoprecipitation,Western Blot,Immunocytochemistry
Conjugate/TagUnconjugated
IsotypeIgG
HostGoat
ReactivityMouse
TargetTGF-beta RI/ALK-5
Quantity100 ug (also 25 ug)
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ClonalityPolyclonal
ImmunogenS. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse TGF¿ß RI/ALK-5, Ala21-Glu121, Accession # BAA05023
ConcentrationLYOPH
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution
NCBI Full Gene Nametransforming growth factor beta receptor 1
NCBI Gene AliasesAAT5, ACVRLK4, ALK-5, ALK5, ESS1, LDS1, LDS1A, LDS2A, MSSE, SKR4, TBR-i, TBRI, TGFR-1, tbetaR-I

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects mouse TGF¿ß RI/ALK-5 in direct ELISAs and Western blots. In direct ELISAs, approximately 50% cross-reactivity with recombinant human (rh) TGF¿ß RI is observed, and less than 2% cross-reactivity with recombinant mouse TGF¿ß RII and rhTGF¿ß RIII is observed.

Sizes Available: 100 ug (also 25 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Differential IL18 signaling via IL18 receptor and Na-Cl co-transporter discriminating thermogenesis and glucose metabolism regulationNature communicationsDecember 8, 2022Zhang X, Luo S, Wang M, Cao Q, Zhang Z, Huang Q, Li J, Deng Z, Liu T, Liu CL, et al.lysates (0.25 mg) were subsequently incubated overnight at 4 °C with goat anti-IL18r antibody (10 μg, AF587, R&D Systems), rabbit anti-NCC antibody (10 μg, AB3553, Millipore), or IgG isotype control antibody

(2) Coco is a dual activity modulator of TGFβ signalingDevelopment (Cambridge, England)August 1, 2015Deglincerti A, Haremaki T, Warmflash A, Sorre B, Brivanlou AH.used were anti-HA (Abcam, ab18181), anti-Alk2 (LifeSpan Biosciences, LS-B2010), antiAlk5 (R&D Systems, AF587), anti-Flag (Sigma-Aldrich, F3165, F7425) and anti-V5 (Abcam, ab9116). Acknowledgements We would like

(3) Augmented cytoplasmic Smad4 induces acceleration of TGF-beta1 signaling in renal tubulointerstitial cells of hereditary nephrotic ICGN mice with chronic renal fibrosis; possible role for myofibroblastic differentiationCell and tissue researchFebruary 1, 2004Goto Y, Manabe N, Uchio-Yamada K, Yamaguchi-Yamada M, Inoue N, Yamamoto Y, Ogura A, Nagano N, Miyamoto H.

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TGF-beta RI/ALK-5 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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TGF-beta RI/ALK-5 Antibody from R&D Systems, a Bio-Techne Brand

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