CCL22/MDC Antibody AF439 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemCCL22/MDC Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $519.00Supplier Page View Company Product Page
Catalog NumberAF439
ApplicationsFlow Cytometry,Immunohistochemistry,Western Blot,In vivo assay,Neutralization,Functional Assay
Quantity100 ug (also 25 ug)
ReactivityMouse (Ms)
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution
NCBI Full Gene NameC-C motif chemokine ligand 22
NCBI Gene AliasesA-152E5.1, ABCD-1, DC/B-CK, MDC, SCYA22, STCP-1
PurityAntigen Affinity-purified
ConcentrationLYOPH
ImmunogenE. coli-derived recombinant mouse CCL22/MDC, Gly25-Ser92, Accession # Q9QZU2
ClonalityPolyclonal
IsotypeIgG
TargetCCL22/MDC
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
Conjugate/TagUnconjugated
HostGoat

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects mouse CCL22/MDC in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross-reactivity with recombinant human CCL22/MDC is observed.

Sizes Available: 100 ug (also 25 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Dendritic cells regulate the innate-adaptive balance in lymph nodes for optimal host defenseCellJanuary 22, 2026Jessica Y. Huang, Michael Y. Gernerpolyclonal anti-CCL21/6Ckine,R&D Systems,CAT# AF457 Goat polyclonal anti-CCL22/MDC,R&D Systems,CAT# AF439 Biotin Rat monoclonal anti-CCR7 (clone 4B12),Biolegend,CAT# 120104 PE Rat monoclonal anti-CD3 (clone

(2) TRAIL agonists rescue mice from radiation-induced lung, skin, or esophageal injuryJournal of Clinical InvestigationJanuary 14, 2025Jillian Strandberg, Anna Louie, Seulki Lee, Marina Hahn, Praveen Srinivasan, Andrew George, Arielle De La Cruz, Leiqing Zhang, Liz Hernandez Borrero, Kelsey E. Huntington, et al.of 20 Gy with shielding of other organs and were treated with either 20 μg of anti-CCL22 antibody (AF439, R&D Systems Inc.) dissolved in 500 μL of sterile normal saline via i.p. injection every other day for

(3) TRAIL agonists rescue mice from radiation-induced lung, skin, or esophageal injuryJ Clin InvestJanuary 14, 2025Jillian Strandberg, Anna Louie, Seulki Lee, Marina Hahn, Praveen Srinivasan, Andrew George, Arielle De La Cruz, Leiqing Zhang, Liz Hernandez Borrero, Kelsey E. Huntington, et al.of 20 Gy with shielding of other organs and were treated with either 20 μg of anti-CCL22 antibody (AF439, R&D Systems Inc.) dissolved in 500 μL of sterile normal saline via i.p. injection every other day for

(4) CCR4 and CCR7 differentially regulate thymocyte localization with distinct outcomes for central toleranceeLifeJune 2, 2023Li Y, Guaman Tipan P, Selden HJ, Srinivasan J, Hale LP, Ehrlich LIR.

(5) PGE(2)-EP2/EP4 signaling elicits immunosuppression by driving the mregDC-Treg axis in inflammatory tumor microenvironmentCell reportsJune 7, 2022Thumkeo D, Punyawatthananukool S, Prasongtanakij S, Matsuura R, Arima K, Nie H, Yamamoto R, Aoyama N, Hamaguchi H, Sugahara S, et al.

(6) Prolactin enhances T regulatory cell promotion of breast cancer through the long form prolactin receptorTranslational oncologyNovember 1, 2021Chen KE, Ghosh M, Rivera L, Lin S, Kumar A, Swaminathan S, Lorenson MY, Walker AM.

(7) Cardiomyocyte Expression of ZO-1 Is Essential for Normal Atrioventricular Conduction but Does Not Alter Ventricular FunctionCirculation researchJuly 3, 2020Zhang J, Vincent KP, Peter AK, Klos M, Cheng H, Huang SM, Towne JK, Ferng D, Gu Y, Dalton ND, et al.Connexin 43,Invitrogen,71-0700,1:500,, β-catenin,Abcam,ab16051,1:100,, Y-catenin,ThermoFisher,PA5-17320,1:50,, N-cad,BD Biosciences,610920,1:100,, contactin-2,R & D Systems,AF439,1:50,, donkey anti-Rabbit Alex-488,Jackson Lab,711-545-152,1:100,, anti-Rabbit Alex-647,Jackson Lab,711-605-152,1:200,, cy3

(8) Eosinophil recruitment is dynamically regulated by interplay among lung dendritic cell subsets after allergen challengeNature communicationsSeptember 24, 2018Yi S, Zhai J, Niu R, Zhu G, Wang M, Liu J, Huang H, Wang Y, Jing X, Kang L, et al.from Miltenyi Biotec. Purified neutralizing antibodies to CCL17/TARC (Cat: AF529) and CCL22/MDC (Cat: AF439), were obtained from R&D Systems. Purified blocking antibody against CD4 (Clone GK1.5) was from BioXcell.

(9) IL-4/CCL22/CCR4 axis controls regulatory T-cell migration that suppresses inflammatory bone loss in murine experimental periodontitisJournal of bone and mineral research : the official journal of the American Society for Bone and Mineral ResearchMarch 1, 2015Araujo-Pires AC, Vieira AE, Francisconi CF, Biguetti CC, Glowacki A, Yoshizawa S, Campanelli AP, Trombone AP, Sfeir CS, Little SR, et al.

(10) Defective immunoregulation in RSV vaccine-augmented viral lung disease restored by selective chemoattraction of regulatory T cellsProceedings of the National Academy of Sciences of the United States of AmericaFebruary 19, 2013Loebbermann J, Durant L, Thornton H, Johansson C, Openshaw PJ.

(11) Prevention of murine autoimmune diabetes by CCL22-mediated Treg recruitment to the pancreatic isletsThe Journal of clinical investigationAugust 1, 2011Montane J, Bischoff L, Soukhatcheva G, Dai DL, Hardenberg G, Levings MK, Orban PC, Kieffer TJ, Tan R, Verchere CB.

(12) Comprehensive assessment of chemokine expression profiles by flow cytometryThe Journal of clinical investigationMarch 1, 2010Eberlein J, Nguyen TT, Victorino F, Golden-Mason L, Rosen HR, Homann D.

(13) Allergic pulmonary inflammation in mice is dependent on eosinophil-induced recruitment of effector T cellsThe Journal of experimental medicineMarch 17, 2008Jacobsen EA, Ochkur SI, Pero RS, Taranova AG, Protheroe CA, Colbert DC, Lee NA, Lee JJ.

(14) The direct action of 1alpha,25(OH)2-vitamin D3 on purified mouse Langerhans cellsCellular immunologyFebruary 1, 2007Fujita H, Asahina A, Komine M, Tamaki K.

(15) Immunosuppressive effects of CCL17 on pulmonary antifungal responses during pulmonary invasive aspergillosisInfection and immunityNovember 1, 2005Carpenter KJ, Hogaboam CM.

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CCL22/MDC Antibody

CCL22/MDC Antibody

CCL22/MDC Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (15)

Reviews

CCL22/MDC Antibody from R&D Systems, a Bio-Techne Brand

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