Mouse CXCL2/MIP-2 Antibody from R&D Systems, a Bio-Techne Brand

Yes, the CXCL2/GRO beta/MIP-2 antibody has been utilized in studies examining the regulation of CXCL2 expression during Mycobacterium tuberculosis infection. Research has shown that CXCL2 is modulated through the Hippo signaling pathway, which is activated during such infections, highlighting its role in directing immune responses and inflammation (boro2016).

The CXCL2/GRO beta/MIP-2 antibody has been demonstrated to effectively neutralize CXCL2 in vivo, as evidenced by studies where its administration significantly reduced inflammation and improved outcomes in models of Bacillus endophthalmitis (mursalin2021).

The CXCL2/GRO beta/MIP-2 antibody has been shown to work in various applications, including Western blotting, immunocytochemistry, and immunohistochemistry. It has been used to detect CXCL2 in different experimental contexts, such as in studies of tissue remodeling during tooth eruption and in inflammatory responses in the respiratory system (makino2021, nagano2014).

This antibody is highly specific for mouse CXCL2/MIP-2, with less than 10% cross-reactivity observed with recombinant human GRO beta and other mouse chemokines such as GRO gamma, KC, and LIX in direct ELISAs and Western blots. This specificity makes it a reliable tool for studying mouse models (huebener2015).