IL-10 R alpha Antibody AF-474-NA from R&D Systems, a Bio-Techne Brand

Product Specs
ItemIL-10 R alpha Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $499.00Supplier Page View Company Product Page
Catalog NumberAF-474-NA
NCBI Gene AliasesCD210a, HIL-10R, IL-10R1, IL10R, mIL-10R, CDw210a, CDW210A, IL-10RA, CDw210, Il10r, CD210
ApplicationsFlow Cytometry,Western Blot,Neutralization,Immunocytochemistry,Functional Assay
TargetIL-10 R alpha
ReactivityMouse,Rat
HostGoat
Quantity100 ug (also 25 ug)
Conjugate/TagUnconjugated
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
IsotypeIgG
NCBI Full Gene Nameinterleukin 10 receptor subunit alpha, interleukin 10 receptor, alpha
ClonalityPolyclonal
ImmunogenS. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse IL-10 R alpha, Thr24-Asn238 (Lys188Arg and Glu222Gly), Accession # Q61727
ConcentrationLYOPH
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects mouse IL-10 R alpha in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 25% cross-reactivity with recombinant human IL-10 R alpha is observed.

Sizes Available: 100 ug (also 25 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Interleukin-10 enhances activity of ventral tegmental area dopamine neurons resulting in increased dopamine releaseBrain, Behavior, and ImmunityOctober 1, 2023Joakim W. Ronström, Stephanie B. Williams, Andrew Payne, Daniel J. Obray, Caylor Hafen, Matthew Burris, K. Scott Scott Weber, Scott C. Steffensen, Jordan T. YorgasonCAT# AB9702). Antibody labeling protocol was used to label IL-10R (alpha) (Novus Biologicals, Cat # AF-474-NA) and TH. The anti-IL-10R (alpha) antibody was conjugated using a CF488 labeling kit (Biotium, CAT#92211).

(2) IL-10 normalizes aberrant amygdala GABA transmission and reverses anxiety-like behavior and dependence-induced escalation of alcohol intakeProg NeurobiolApril 1, 2021Patel RR, Wolfe SA, Bajo M, Abeynaike S, Pahng A, Borgonetti V, D'Ambrosio S, Nikzad R, Edwards S, Paust S, et al.milk with primary antibody at 4°C. The primary antibody was mouse IL-10Rα (1:2500; R&D Systems; Cat # AF-474-NA). Membranes were washed and incubated with species-specific peroxidase-conjugated secondary antibodies

(3) Single cell analysis reveals immune cell-adipocyte crosstalk regulating the transcription of thermogenic adipocyteseLifeOctober 23, 2019Rajbhandari P, Arneson D, Hart SK, Ahn IS, Diamante G, Santos LC, Zaghari N, Feng AC, Thomas BJ, Vergnes L, et al.

(4) Involvement of Interleukin-10 in Analgesia of Electroacupuncture on Incision PainEvidence-based complementary and alternative medicine : eCAMJanuary 1, 2019Dai WJ, Sun JL, Li C, Mao W, Huang YK, Zhao ZQ, Zhang YQ, Lü N.

(5) The Dendritic Cell Receptor DNGR-1 Promotes the Development of Atherosclerosis in MiceCirculation researchJuly 21, 2017Haddad Y, Lahoute C, Clément M, Laurans L, Metghalchi S, Zeboudj L, Giraud A, Loyer X, Vandestienne M, Wain-Hobson J, et al.

(6) Alternative activation-skewed microglia/macrophages promote hematoma resolution in experimental intracerebral hemorrhageNeurobiology of diseaseJuly 1, 2017Chang CF, Wan J, Li Q, Renfroe SC, Heller NM, Wang J.

(7) Re-evaluation of IL-10 signaling reveals novel insights on the contribution of the intracellular domain of the IL-10R2 chainPloS oneJanuary 1, 2017Wilbers RHP, van Raaij DR, Westerhof LB, Bakker J, Smant G, Schots A.

(8) Mesenchymal Stem Cell-Educated Macrophages Ameliorate LPS-Induced Systemic ResponseMediators of inflammationJanuary 1, 2016Hu Y, Qin C, Zheng G, Lai D, Tao H, Zhang Y, Qiu G, Ge M, Huang L, Chen L, et al.antibody, R&D Systems, MAB417), IL10 receptor antibody (10 ng/mL) (mouse polyclonal antibody, R&D Systems, AF-474-NA), or mouse IgG1 control (10 ng/mL) (R&D Systems). After 48 h, cells were replenished with fresh medium

(9) IL4I1 Is a Novel Regulator of M2 Macrophage Polarization That Can Inhibit T Cell Activation via L-Tryptophan and Arginine Depletion and IL-10 ProductionPloS oneJanuary 1, 2015Yue Y, Huang W, Liang J, Guo J, Ji J, Yao Y, Zheng M, Cai Z, Lu L, Wang J.

(10) Neuronal synapse formation induced by microglia and interleukin 10PloS oneJanuary 1, 2013Lim SH, Park E, You B, Jung Y, Park AR, Park SG, Lee JR.IL-6 (506-RL), and rat IL-4 (504-RL). The following antibodies were used: anti-mouse IL-10 receptor α (AF-474-NA), anti-rat TNFα (MAB510) obtained from R&D systems (Minneapolis, MN, USA); anti-CD11b/c (ab1211), anti-GFAP

(11) Interleukin-10 production by tumor infiltrating macrophages plays a role in Human Papillomavirus 16 tumor growthBMC immunologyJune 7, 2010Bolpetti A, Silva JS, Villa LL, Lepique AP.R&D Systems, Minneapolis, MN) alternated with intraperitoneal doses of 10 μg of anti-IL-10R antibody (AF-474-NA, R&D Systems, Minneapolis, MN) spaced by 4 days. The first dose was given in the same day as the TC-1

(12) IL-10 receptor and coreceptor expression in quiescent and activated hepatic stellate cellsAmerican journal of physiology. Gastrointestinal and liver physiologyJune 1, 2002Mathurin P, Xiong S, Kharbanda KK, Veal N, Miyahara T, Motomura K, Rippe RA, Bachem MG, Tsukamoto H.

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IL-10 R alpha Antibody

IL-10 R alpha Antibody

IL-10 R alpha Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (12)

Reviews

IL-10 R alpha Antibody from R&D Systems, a Bio-Techne Brand

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