IL-6 Antibody AB-406-NA from R&D Systems, a Bio-Techne Brand

Product Specs
ItemIL-6 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $529.00Supplier Page View Company Product Page
Catalog NumberAB-406-NA
NCBI Gene AliasesCDF, HSF, BSF-2, Il-6, IL-6, IFNB2, HGF, BSF2, IFN-beta-2
ApplicationsImmunohistochemistry,Western Blot,Neutralization,Cell Culture
TargetIL-6
Quantity1 mg
Conjugate/TagUnconjugated
ReactivityMouse,Transgenic Mouse
HostGoat
IsotypeIgG
NCBI Full Gene Nameinterleukin 6
ClonalityPolyclonal
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose
ImmunogenE. coli-derived recombinant mouse IL-6, Phe25-Thr211, Accession # P08505
ConcentrationLYOPH
PurityProtein A or G purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects mouse IL-6 in direct ELISAs and Western blots. In direct ELISAs, approximately 30% cross-reactivity with recombinant rat IL-6 is observed and less than 5% cross-reactivity with recombinant human IL-6, recombinant feline IL-6, recombinant bovine IL-6, and recombinant porcine IL-6 is observed.

Sizes Available: 1 mg

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) p53-loss induced prostatic epithelial cell plasticity and invasion is driven by a crosstalk with the tumor microenvironmentCell death & diseaseJanuary 26, 2025Yanushko D, German Falcon B, El Bizri R, Pervizou D, Dolgos R, Keime C, Ye T, Thibault-Carpentier C, Le Magnen C, Henri S, et al.(MedChemExpress, HY-50856), with control IgG (R&D Systems; AB-108) or IL-6 neutralizing antibody (R&D Systems; AB-406-NA), or with “organoid medium” supplemented with IL-6 (at a final concentration of 2 or 4 ng/mL) (PeproTech,

(2) Anti-diabetic effects of GLP1 analogs are mediated by thermogenic interleukin-6 signaling in adipocytesCell reports. MedicineNovember 15, 2022Gutierrez AD, Gao Z, Hamidi V, Zhu L, Saint Andre KB, Riggs K, Ruscheinsky M, Wang H, Yu Y, Miller C 3rd, et al.9139 Anti-pSTAT3,Cell Signaling,Cat. # 9145 Anti-UCP1,Sigma,Cat. # U6382 IL-6 antibody BF09,R&D Systems,"Cat. # AB-406-NA," Donkey Alexa 488-IgG,Jackson ImmunoResearch,Cat. # A11055 Donkey Alexa Cy3-IgG,Jackson ImmunoResearch,Cat.

(3) Bi-phasic effect of gelatin in myogenesis and skeletal muscle regenerationDisease models & mechanismsDecember 1, 2021Liu X, Zu E, Chang X, Ma X, Wang Z, Song X, Li X, Yu Q, Kamei KI, Hayashi T, et al.were purchased from Proteintech (Wuhan, Hubei, China). The monoclonal neutralization Abs against IL-6 (AB-406-NA) and TNFα (AB-410-NA), and recombinant mouse proteins IL-6 and TNFα, were purchased from R&D Systems

(4) Tyrosyl phosphorylation of PZR promotes hypertrophic cardiomyopathy in PTPN11-associated Noonan syndrome with multiple lentiginesJCI insightAugust 6, 2020Yi JS, Perla S, Enyenihi L, Bennett AM.

(5) Exercise Protects Against Olanzapine-Induced Hyperglycemia in Male C57BL/6J MiceScientific reportsJanuary 15, 2018Castellani LN, Peppler WT, Miotto PM, Bush N, Wright DC.ELISA from Sigma (Oakville, Ontario)(cat. No. RAB0308). Mouse IL-6 neutralizing antibodies (cat. No. AB-406-NA) and IgG control (cat. No. AB-108-C) were from R&D Systems (Minneapolis, MN). Recombinant murine IL-6

(6) TGF-β-induced IL-6 prevents development of acute lung injury in influenza A virus-infected F508del CFTR-heterozygous miceAmerican journal of physiology. Lung cellular and molecular physiologyJune 1, 2015Woods PS, Tazi MF, Chesarino NM, Amer AO, Davis IC.formalin-fixed, paraffin-embedded lung tissue (31). IL-6 was detected using a goat polyclonal antibody (AB-406-NA; R & D Systems, Minneapolis, MN). Bound antibody was detected using biotinylated anti-goat immunoglobulin

(7) Retinol-binding protein 4 inhibits insulin signaling in adipocytes by inducing proinflammatory cytokines in macrophages through a c-Jun N-terminal kinase- and toll-like receptor 4-dependent and retinol-independent mechanismMolecular and cellular biologyMay 1, 2012Norseen J, Hosooka T, Hammarstedt A, Yore MM, Kant S, Aryal P, Kiernan UA, Phillips DA, Maruyama H, Kraus BJ, et al.and monocyte chemoattractant protein 1 (MCP-1) were obtained from R&D Systems (catalog no. AB-410-NA, AB406-NA, and AB-479-NA). Cocultured 3T3L1 adipocytes and RAW264.7 macrophages were serum starved for 2 h, pretreated

(8) Maladaptive role of IL-6 in ischemic acute renal failureJournal of the American Society of Nephrology : JASNNovember 1, 2005Kielar ML, John R, Bennett M, Richardson JA, Shelton JM, Chen L, Jeyarajah DR, Zhou XJ, Zhou H, Chiquett B, et al.by the ELISA method (Endogen). In addition, we used polyclonal goat neutralizing anti-murine IL-6 (AB-406-NA) and control goat IgG (AB-108-C) from R&D systems (www.rndsystems.com). These antibody preparations

(9) "A novel T cell cytokine, secreted osteoclastogenic factor of activated T cells, induces osteoclast formation in a RANKL-independent manner"Arthritis and rheumatismJanuary 1, 0001"Rifas L, Weitzmann MN."neutralizing TNFα antibody (20 μg/mL) or IL-6 antibodies (20 μg/mL) from R&D Systems (AF-410-NA and AB-406-NA respectively).. Osteoclasts were quantitated under light microscopy and normalized for number of nuclei.

(10) Heterogeneity in old fibroblasts is linked to variability in reprogramming and wound healingNatureJanuary 1, 0001"Mahmoudi S, Mancini E, Xu L, Moore A, Jahanbani F, Hebestreit K, Srinivasan R, Li X, Devarajan K, Prélot L, et al."polyclonal goat IgG (R&D systems, AB-108-C), goat polyclonal mouse anti-IL-6 blocking antibody (R&D systems, AB-406-NA) and goat polyclonal mouse anti-TNF blocking antibody (R&D systems, AB-410-NA). For all experiments,

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IL-6 Antibody

IL-6 Antibody

IL-6 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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IL-6 Antibody from R&D Systems, a Bio-Techne Brand

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