PDGF-BB Antibody AB-220-NA from R&D Systems, a Bio-Techne Brand

Product Specs
ItemPDGF-BB Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $489.00Supplier Page View Company Product Page
Catalog NumberAB-220-NA
NCBI Gene AliasesSIS, IBGC5, c-sis, SSV, PDGF-2, PDGF2
ApplicationsWestern Blot,Neutralization
Conjugate/TagUnconjugated
IsotypeIgG
HostGoat
TargetPDGF-BB
Quantity1 mg
ReactivityHuman
NCBI Full Gene Nameplatelet derived growth factor subunit B
ClonalityPolyclonal
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose
ImmunogenE. coli-derived recombinant human PDGF-BB, Ser82-Thr190, Accession # P01127
ConcentrationLYOPH
PurityProtein A or G purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects human PDGF-BB in direct ELISAs and Western blots. In direct ELISAs, approximately 100% cross-reactivity with recombinant human (rh) PDGF-AB is observed, approximately 50% cross-reactivity with recombinant rat PDGF-B and natural porcine PDGF is observed, and less than 10% cross-reactivity with rhPDGF-A is observed.

Sizes Available: 1 mg

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Engagement of the CXCL12-CXCR4 Axis in the Interaction of Endothelial Progenitor Cell and Smooth Muscle Cell to Promote Phenotype Control and Guard Vascular HomeostasisInternational journal of molecular sciencesJanuary 14, 2022Mause SF, Ritzel E, Deck A, Vogt F, Liehn EA.

(2) RASSF1A inhibits PDGFB-driven malignant phenotypes of nasopharyngeal carcinoma cells in a YAP1-dependent mannerCell death & diseaseOctober 14, 2020Liang YY, Deng XB, Lin XT, Jiang LL, Huang XT, Mo ZW, Yuan YW, Teh MT.Immunoglobulin G (IgG) control (AB-108-C, R&D Systems, USA) or neutralizing antibody against PDGF-BB (AB-220-NA, R&D Systems, USA) or latrunculin b (LTB, ab144291, Abcam, UK) 12 h after plating. The PDGF-BB level

(3) Acidic fibroblast growth factor underlies microenvironmental regulation of MYC in pancreatic cancerThe Journal of experimental medicineAugust 3, 2020Bhattacharyya S, Oon C, Kothari A, Horton W, Link J, Sears RC, Sherman MH.PDGF-AA neutralizing antibody (R&D Systems, MAB221); human PDGF-BB neutralizing antibody (R&D Systems, AB-220-NA); and human/mouse Wnt-3a neutralizing antibody (R&D Systems, MAB9025). Plasmids HA-AKT DN (K17M) was

(4) Long noncoding RNA LERFS negatively regulates rheumatoid synovial aggression and proliferationThe Journal of clinical investigationOctober 1, 2018Zou Y, Xu S, Xiao Y, Qiu Q, Shi M, Wang J, Liang L, Zhan Z, Yang X, Olsen N, et al.from patients with RA reduced LERFS expression, however, addition of a PDGF-neutralizing antibody (50 ng/ml, AB-220-NA; R&D Systems) largely reversed LERFS expression (Figure 1D). Since a previous report showed that PDGF

(5) Hypoxia Differentially Regulates Arterial and Venous Smooth Muscle Cell MigrationPloS oneJanuary 1, 2015Chanakira A, Kir D, Barke RA, Santilli SM, Ramakrishnan S, Roy S.

(6) Platelet-Derived Growth Factor-B Enhances Glioma Angiogenesis by Stimulating Vascular Endothelial Growth Factor Expression in Tumor Endothelia and by Promoting Pericyte RecruitmentThe American Journal of PathologyApril 1, 2003Ping Guo, Bo Hu, Weisong Gu, Li Xu, Degui Wang, Hui-Jen Su Huang, Webster K. Cavenee, Shi-Yuan ChengPDGF-B proteins. The lower wells also included either 50 ␮g/ml of a neutralizing anti-PDGF-B antibody (AB-220-NA) or a purified goat IgG protein (R&D Systems). Human recombinant VEGF proteins (10 ng/ml) or a neutralizing

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PDGF-BB Antibody

PDGF-BB Antibody

PDGF-BB Antibody

PDGF-BB Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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PDGF-BB Antibody from R&D Systems, a Bio-Techne Brand

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