Human IL-5 R alpha /CD125 Antibody AF-253-NA from R&D Systems, a Bio-Techne Brand

Product Specs
ItemHuman IL-5 R alpha /CD125 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $479.00Supplier Page View Company Product Page
Catalog NumberAF-253-NA
Quantity100 ug (also 25 ug)
ApplicationsFlow Cytometry,Western Blot,Neutralization,Immunocytochemistry,CyTOF-ready
Conjugate/TagUnconjugated
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ConcentrationLYOPH
PurityAntigen Affinity-purified
IsotypeIgG
HostGoat
TargetIL-5 R alpha/CD125
ReactivityHuman
Antibody TypePrimary Antibodies
ClonalityPolyclonal
ImmunogenS. frugiperda insect ovarian cell line Sf 21-derived recombinant human IL-5 R alpha /CD125
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution
NCBI Full Gene Nameinterleukin 5 receptor subunit alpha
NCBI Gene AliasesCD125, CDw125, HSIL5R3, IL5R

Specifications/Features

Available conjugates: Unconjugated

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Three lysine residues in the common β chain of the interleukin-5 receptor are required for Janus kinase (JAK)-dependent receptor ubiquitination, endocytosis, and signalingThe Journal of biological chemistryNovember 18, 2011Lei JT, Mazumdar T, Martinez-Moczygemba M.

(2) Separate endocytic pathways regulate IL-5 receptor internalization and signalingJournal of leukocyte biologyAugust 1, 2008Lei JT, Martinez-Moczygemba M.

(3) T lymphocyte-mediated changes in airway smooth muscle responsiveness are attributed to induced autocrine release and actions of IL-5 and IL-1betaThe Journal of allergy and clinical immunologyOctober 1, 2002Hakonarson H, Whelan R, Leiter J, Kim C, Chen M, Campbell D, Grunstein MM.

(4) Interleukin-5 in growth and differentiation of blood eosinophil progenitors in asthma: effect of glucocorticoidsBritish Journal of PharmacologyDecember 1, 2001Han-Pin Kuo, Chun-Hua Wang, Horng-Chyuan Lin, Kuo-Shiung Hwang, Shu-Liang Liu, Kian Fan ChungMinneapolis, MN, U.S.A.), or anti-IL-5Ra monoclonal neutralizing antibody (2.5 mg ml71; Catalogue number AF-253-NA, R & D Systems, Minneapolis, MN, U.S.A.), or dexamethasone (1076 M). In the studies with dexamethasone,

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IL-5 R alpha/CD125 Antibody

Human IL-5 R alpha /CD125 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (4)

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Human IL-5 R alpha /CD125 Antibody from R&D Systems, a Bio-Techne Brand

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