GM-CSF Antibody AF-215-NA from R&D Systems, a Bio-Techne Brand

Product Specs
ItemGM-CSF Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $529.00Supplier Page View Company Product Page
Catalog NumberAF-215-NA
NCBI Gene AliasesCSF, GMCSF
ApplicationsImmunohistochemistry,Western Blot,Neutralization,Immunocytochemistry,ELISA Capture
HostGoat
Conjugate/TagUnconjugated
IsotypeIgG
Quantity100 ug (also 25 ug)
TargetGM-CSF
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ReactivityHuman,Mouse
NCBI Full Gene Namecolony stimulating factor 2
ClonalityPolyclonal
ImmunogenE. coli-derived recombinant human GM-CSF, Ala18-Glu144, Accession # P04141
ConcentrationLYOPH
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects human GM-CSF in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross-reactivity with recombinant mouse GM-CSF is observed. Neutralizes the biological activity of both recombinant human GM-CSF and natural human GM-CSF.

Sizes Available: 100 ug (also 25 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Evaluation of the α-casein (CSN1S1) locus as a potential target for a site-specific transgene integrationScientific reportsMay 14, 2022Smirnov AV, Kontsevaya GV, Shnaider TA, Yunusova AM, Feofanova NA, Gerlinskaya LA, Serova IA, Serov OL, Battulin NR.

(2) A digital single-molecule nanopillar SERS platform for predicting and monitoring immune toxicities in immunotherapyNature communicationsFebruary 17, 2021Li J, Wuethrich A, Sina AAI, Cheng HH, Wang Y, Behren A, Mainwaring PN, Trau M.

(3) Human neutrophils depend on extrinsic factors produced by monocytes for their survival response to TLR4 stimulationInnate immunityNovember 1, 2019SenGupta S, Rane MJ, Uriarte SM, Woolley C, Mitchell TC.(clone DREG-56, BioLegend); neutralizing Ab against human IL-8 (cat. no. MAB208-100); GM-CSF (cat. no. AF-215-NA) and corresponding isotypes (R&D systems); control mouse (clone 11711); and goat IgG (AB-108-C), were

(4) Decidual GM-CSF is a critical common intermediate necessary for thrombin and TNF induced in-vitro fetal membrane weakeningPlacentaDecember 1, 2014Kumar D, Moore RM, Nash A, Springel E, Mercer BM, Philipson E, Mansour JM, Moore JJ.

(5) Low concentrations of recombinant granulocyte macrophage-colony stimulating factor derived from Chinese hamster ovary cells augments long-term bioactivity with delayed clearance in vitroCytokineAugust 1, 2014Hashimoto A, Tanaka T, Itoh Y, Yamagata A, Kitamura N, Tazawa R, Nakagaki K, Nakata K.

(6) GM-CSF enhances tumor invasion by elevated MMP-2, -9, and -26 expressionCancer medicineApril 1, 2013Gutschalk CM, Yanamandra AK, Linde N, Meides A, Depner S, Mueller MM.Penicillin/Streptomycin (100 U/100 μg/mL) (D1), or D1 containing 2 μg/mL GM-CSF neutralizing antibody (#AF-215-NA, R&D Systems, Minneapolis, Minnesota) or irrelevant antibody (Mouse IgG1, #M7894, Sigma-Aldrich, Steinheim,

(7) Prolonged, granulocyte-macrophage colony-stimulating factor-dependent, neutrophil survival following rheumatoid synovial fibroblast activation by IL-17 and TNFalphaArthritis research & therapyJanuary 1, 2008Parsonage G, Filer A, Bik M, Hardie D, Lax S, Howlett K, Church LD, Raza K, Wong SH, Trebilcock E, et al.from Peprotech (London, UK), monoclonal anti-human GM-CSF (MAB215) and polyclonal anti-human GM-CSF (AF215NA) were from R&D Systems (Abingdon, UK), and recombinant IFNβ was from Biosource (Paisley, UK). Type I

(8) Apoptotic neutrophils release macrophage migration inhibitory factor upon stimulation with tumor necrosis factor-alphaThe Journal of biological chemistrySeptember 15, 2006Daryadel A, Grifone RF, Simon HU, Yousefi S.

(9) Secretory IgA induces antigen-independent eosinophil survival and cytokine production without inducing effector functionsThe Journal of allergy and clinical immunologyOctober 1, 2005Bartemes KR, Cooper KM, Drain KL, Kita H.

(10) Toxoplasma gondii induces granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor secretion by human fibroblasts: implications for neutrophil apoptosisInfection and immunityNovember 1, 2002Channon JY, Miselis KA, Minns LA, Dutta C, Kasper LH.

(11) Bleomycin stimulates lung fibroblast and epithelial cell lines to release eosinophil chemotactic activityThe European respiratory journalNovember 1, 2000Sato E, Koyama S, Robbins RA.