TERF2IP Antibody

Product Specs
ItemTERF2IP Antibody - BSA Free
CompanyNovus Biologicals, a Bio-Techne Brand
Price $479.00Supplier Page View Company Product Page
Catalog NumberNB100-292
ImmunogenAntibody was generated using recombinant full length human RAP1 (Telomeric repeat binding factor 2 interacting protein 1) according to entry NP_061848.2
NCBI Gene AliasesRAP1, DRIP5
Concentration1.0 mg/ml
Conjugate/TagUnconjugated
TargetTERF2IP
FormatTris-Citrate/Phosphate (pH 7.0 - 8.0)
HostRabbit
Quantity100 ul
ApplicationsFISH,Immunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence
ReactivityHuman
NCBI Full Gene NameTERF2 interacting protein
ClonalityPolyclonal
PurityImmunogen affinity purified
Research AreaCellular Markers, Chromatin Research, DNA Repair, Endosome Markers, Lysosome Markers
IsotypeIgG
Antibody TypePrimary Antibodies
StorageStore at 4C. Do not freeze

Specifications/Features

Available conjugates: Unconjugated

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Novus Biologicals, a Bio-Techne Brand

United States: 10771 E Easter Ave

Centennial, Colorado 80112

United States

Phone:
303-730-1950
888-506-6887

Email: novus@novusbio.com

Company Profile

Website: https://www.novusbio.com

(1) TRF1 and TRF2 form distinct shelterin subcomplexes at telomeresCell reportsSeptember 23, 2025Janovič T, Perez GI, Boelting G, Schmidt JC.(Novus #NB100–56506, 1:1,500 dilution or Novus #NB110–57130, 1:1,500 dilution), anti-TERF2IP (Novus #NB100–292, 1:1,000 dilution), anti-TPP1 (Bethyl #A303–069A, 1:2,000 dilution), anti-POT1 (Proteintech #10581–1-AP,

(2) TRF1 and TRF2 form distinct shelterin subcomplexes at telomeresbioRxivDecember 26, 2024Tomáš Janovič, Gloria I. Perez, Jens C. Schmidtantibodies used in this study: anti-TERF2 (Novus #NB100–56506, 1:1,500 dilution), anti-TERF2IP (Novus #NB100–292, 1:1,000 dilution), anti-TPP1 (Bethyl #A303–069A, 1:2,000 dilution), anti-POT1 (Proteintech #10581–1-AP,

(3) TERRA transcripts localize at long telomeres to regulate telomerase access to chromosome endsScience advancesJune 14, 2024Bettin N, Querido E, Gialdini I, Grupelli GP, Goretti E, Cantarelli M, Andolfato M, Soror E, Sontacchi A, Jurikova K, et al.

(4) The human RAP1 and GFAPɛ proteins increase γ-secretase activity in a yeast model systemG3 (Bethesda, Md.)August 9, 2023Swanson MJ, Lewis KN, Carpenter R, Whetzel A, Bae NS.

(5) TERRA stability is regulated by RALY and polyadenylation in a telomere-specific mannerCell reportsApril 25, 2023Savoca V, Rivosecchi J, Gaiatto A, Rossi A, Mosca R, Gialdini I, Zubovic L, Tebaldi T, Macchi P, Cusanelli E.

(6) Live-cell imaging reveals the dynamics and function of single-telomere TERRA molecules in cancer cellsRNA biologyJanuary 1, 2018Avogaro L, Querido E, Dalachi M, Jantsch MF, Chartrand P, Cusanelli E.used at 1:500 dilution in PBG buffer; for Rap1 detection, anti-TERF2IP antibody (Novus Biologicals, NB100292) was used (1:500 dilution). After antibody incubation, coverslips were washed three times in a 1xPBS

(7) Identification of human TERT elements necessary for telomerase recruitment to telomereseLifeOctober 1, 2014Schmidt JC, Dalby AB, Cech TR.

(8) Hoyeraal-Hreidarsson syndrome caused by a germline mutation in the TEL patch of the telomere protein TPP1Genes & developmentOctober 1, 2014Kocak H, Ballew BJ, Bisht K, Eggebeen R, Hicks BD, Suman S, O'Neil A, Giri N, NCI DCEG Cancer Genomics Research Laboratory., NCI DCEG Cancer Sequencing Working Group., et al.plotted for each TPP1 construct. For IF experiments to detect RAP1, rabbit polyclonal anti-RAP1 (1:500; NB100-292, Novus Biologicals) was used. Telomere FISH of EBV-transformed lymphoblasts was performed with a red

(9) Telomere dysfunction and activation of alternative lengthening of telomeres in B-lymphocytes infected by Epstein-Barr virusOncogeneDecember 5, 2013Kamranvar SA, Chen X, Masucci MG.USA), TPP1 (1:500 ab39042, Abcam, Cambridge, MA, USA), TIN2 (1:250 IMG-282, IMGENEX), RAP-1 (1:1000 NB100-292, Novus Biologicals), ATRX (1:1000 H-300, Sc-15408, Santa Cruz), DAXX (1:1000 D7810, Sigma-Aldrich) and

(10) Molecular basis of telomere syndrome caused by CTC1 mutationsGenes & developmentOctober 1, 2013Chen LY, Majerská J, Lingner J.immunodetection of CTC1-myc and RAP1 using α-mouse anti-myc (9E10) and α-rabbit anti-RAP1 primary antibodies (NB100-292, Novus), respectively. After washing with phosphate-buffered saline, secondary antibodies against mouse

(11) The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivityNatureDecember 13, 2012Nandakumar J, Bell CF, Weidenfeld I, Zaug AJ, Leinwand LA, Cech TR.mouse monoclonal anti-FLAG M2 (Sigma; F1804; 1:500) and rabbit polyclonal anti-RAP1 (Novus Biologicals; NB100–292; 1:500) primary antibodies. For combined immunofluorescence-fluorescence in situ hybridization (IF-FISH)

(12) CTC1 deletion results in defective telomere replication, leading to catastrophic telomere loss and stem cell exhaustionThe EMBO journalMay 16, 2012Gu P, Min JN, Wang Y, Huang C, Peng T, Chai W, Chang S.

(13) Characterization of the DNA binding specificity of Shelterin complexesNucleic acids researchNovember 1, 2011Choi KH, Farrell AS, Lakamp AS, Ouellette MM.

(14) A role for heterochromatin protein 1γ at human telomeresGenes & developmentSeptember 1, 2011Canudas S, Houghtaling BR, Bhanot M, Sasa G, Savage SA, Bertuch AA, Smith S.

(15) TIN2 protein dyskeratosis congenita missense mutants are defective in association with telomeraseThe Journal of biological chemistryJuly 1, 2011Yang D, He Q, Kim H, Ma W, Songyang Z.

(16) ATM mediates cytotoxicity of a mutant telomerase RNA in human cancer cellsCancer researchJuly 1, 2008Stohr BA, Blackburn EH.

(17) Functional diversity of human protection of telomeres 1 isoforms in telomere protection and cellular senescenceCancer researchDecember 15, 2007Yang Q, Zhang R, Horikawa I, Fujita K, Afshar Y, Kokko A, Laiho P, Aaltonen LA, Harris CC.

(18) Telomere maintenance through spatial control of telomeric proteinsMolecular and cellular biologyAugust 1, 2007Chen LY, Liu D, Songyang Z.

(19) A RAP1/TRF2 complex inhibits nonhomologous end-joining at human telomeric DNA endsMolecular cellMay 11, 2007Bae NS, Baumann P.

(20) Human Rif1 protein binds aberrant telomeres and aligns along anaphase midzone microtubulesThe Journal of cell biologyDecember 6, 2004Xu L, Blackburn EH.

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