MOUSE ANTI RAT MHC CLASS II RT1B MCA46G from Bio-Rad (Formerly AbD Serotec)

Product Specs
ItemMOUSE ANTI RAT MHC CLASS II RT1B
CompanyBio-Rad
Price $721.00Supplier Page View Company Product Page
Catalog NumberMCA46G
Quantity1 mg
ApplicationsImmunohistology - Paraffin,Flow Cytometry,Immunohistology - Frozen,Immunofluorescence
ConcentrationIgG concentration 1.0 mg/ml
FormatPurified IgG - liquid
ReactivityRat, Mouse
TargetMHC CLASS II RT1B
IsotypeIgG1
CloneOX-6
HostMouse
ImmunogenRat thymocyte membrane glycoprotein
ClonalityMonoclonal Antibody

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Bio-Rad

Bio-Rad Laboratories, Inc. Life Science Research Group 2000 Alfred Nobel Drive

Hercules, California 94547

United States

Phone: 800-424 6723
800-879 2289

Company Profile

Website: http://discover.bio-rad.com

(1) Polyethylene glycol has immunoprotective effects on sciatic allografts, but behavioral recovery and graft tolerance require neurorrhaphy and axonal fusionNeural regeneration researchApril 1, 2025Smith TA, Zhou L, Ghergherehchi CL, Mikesh M, Yang CZ, Tucker HO, Allgood J, Bushman JS, Bittner GD.(1:100; Novus Biologicals, Cat# NB120- 6405, RRID: AB_791151), mouse anti-rat MHCII (1:100; Bio-Rad, Cat# MCA46GA; RRID: AB_567369), mouse anti-rat neurofilament-medium (NF-M; 1:200; DSHB, Iowa City, IA, USA, Cat#

(2) In vitro high-content screening reveals miR-429 as a protective molecule in photoreceptor degenerationMolecular Therapy - Nucleic AcidsMarch 11, 2025Georgios Petrogiannakis, Irene Guadagnino, Santiago Negueruela, Martina Di Guida, Elena Marrocco, Mariateresa Pizzo, Annalaura Torella, Mariateresa Zanobio, Marianthi Karali, Diego Luis Medina, et al.anti-IBA1 (1:300; 019-19741; Fujifilm Wako Pure Chemical, Osaka, Japan) and anti-MHC class II (1:200; MCA46GA; Bio-Rad, Hercules, CA, USA) primary antibodies were performed for 1 h in 0.3% Triton/4% normal goat

(3) Modulation of cannabinoid receptor 2 alters neuroinflammation and reduces formation of alpha-synuclein aggregates in a rat model of nigral synucleinopathyJournal of NeuroinflammationSeptember 27, 2024Valerie Joers, Benjamin C Murray, Caroline McLaughlin, Danielle Oliver, Hannah E. Staley, Jazmyn Coronado, Cindy Achat-Mendes, Sanam Golshani, Sean D. Kelly, Matthew Goodson, et al.Cat# ab51253, RRID: AB_869973), CD68 (Bio-Rad Cat# MCA341R, RRID: AB_2291300), MHCII (Bio-Rad Cat# MCA46GA, RRID: AB_567369), and CD163 (Bio-Rad Cat# MCA342A, RRID: AB_2074557). Tissue was incubated in appropriate

(4) Non-HLA angiotensin-type-1 receptor autoantibodies mediate the long-term loss of grafted neurons in Parkinson’s disease modelsStem Cell Research & TherapyMay 12, 2024Ana I. Rodríguez-Pérez, Pablo Garrido-Gil, Maria García-Garrote, Ana Muñoz, Juan A. Parga, Jose Luis Labandeira-García, Jannette Rodríguez-PallaresSigma-Aldrich) or mouse monoclonal antibody against OX-6 (as a marker of activated microglia; 1:500; MCA46G; BioRad, Hercules, CA, USA). The sections were subsequently incubated, first for 1 h with the corresponding

(5) Alpha-synuclein inclusion responsive microglia are resistant to CSF1R inhibitionJournal of NeuroinflammationApril 25, 2024Anna C. Stoll, Christopher J. Kemp, Joseph R. Patterson, Michael Kubik, Nathan Kuhn, Matthew Benskey, Megan F. Duffy, Kelvin C. Luk, Caryl E. Sortwell019-09741), mouse anti-major histocompatibility complex-II (MHC Class II RT1B clone OX-6) (1:2000; BioRad, MCA46G). Sections were washed in TBS-Tx and then incubated for 2-h at room temperature with biotinylated secondary

(6) Neuroinflammatory gene expression profiles of reactive glia in the substantia nigra suggest a multidimensional immune response to alpha synuclein inclusionsNeurobiology of DiseaseFebruary 1, 2024Anna C. Stoll, Christopher J. Kemp, Joseph R. Patterson, Jacob W. Howe, Kathy Steece-Collier, Kelvin C. Luk, Caryl E. Sortwell, Matthew J. Benskeyand mouse anti-major histocompatibility complex-II (MHC Class II RT1B clone OX-6) (1:2000; BioRad, MCA46G; RRID: AB_322113). Sections were washed in TBS-Tx and then incubated for 2-h at room temperature with

(7) Microglial depletion does not impact alpha-synuclein aggregation or nigrostriatal degeneration in the rat preformed fibril modelResearch SquareMay 5, 2023Anna C. Stoll, Christopher J. Kemp, Joseph R. Patterson, Michael Kubik, Nathan Kuhn, Matthew Benskey, Megan F. Duffy, Kelvin Luk, Caryl E. Sortwell019–09741), mouse anti-major histocompatibility complex-II (MHC Class II RT1B clone OX-6) (1:2,000; BioRad, MCA46G). Sections were washed in TBS-Tx and then incubated for 2-hours at room temperature with biotinylated

(8) STING Contributes to Cancer-Induced Bone Pain by Promoting M1 Polarization of Microglia in the Medial Prefrontal CortexCancersOctober 22, 2022Zhang X, Li X, Wang W, Zhang Y, Gong Z, Peng Y, Wu J, You X.(1:100, ab177487, Abcam, Cambridge, UK), GFAP (1:100, ab254082, Abcam, Cambridge, UK), and MHCII (1:50, MCA46GA, Bio-rad, Hercules, CA, USA). After incubation and washing with PBS, sections were incubated with secondary

(9) Evaluation of neuroprotective and immunomodulatory properties of mesenchymal stem cells in an ex vivo retinal explant modelJournal of neuroinflammationMarch 2, 2022Reboussin É, Buffault J, Brignole-Baudouin F, Réaux-Le Goazigo A, Riancho L, Olmiere C, Sahel JA, Mélik Parsadaniantz S, Baudouin C.markers,,, CD11b/c,Rabbit,BD Pharmingen,554862 CD45,Mouse,Serotec,MCA43PE CD68,Mouse,Serotec,MCA341R Ia,Mouse,Bio-Rad,MCA46G Isotype control FITC,Armenian hamster,eBioscience,11-4888-81 IgG2a kappa Isotype control,Mouse,eBioscience,45-4724-80 "IgG1,

(10) Neuroinflammation in the medial prefrontal cortex exerts a crucial role in bone cancer painFrontiers in molecular neuroscienceJanuary 1, 2022Li X, Wang W, Zhang X, Gong Z, Tian M, Zhang Y, You X, Wu J.100 and 5% normal donkey serum (NDS) in PBS for 1 h, and incubated overnight with anti-MHCII (1:50, MCA46GA, BIO-RAD), anti-IBA-1 (1:100, ab178847, Abcam), anti-GFAP (1:100, ab254082, Abcam), anti-NEUN (1:100,

(11) AAV-miR-204 Protects from Retinal Degeneration by Attenuation of Microglia Activation and Photoreceptor Cell DeathMolecular Therapy - Nucleic AcidsMarch 6, 2020Marianthi Karali, Irene Guadagnino, Elena Marrocco, Rossella De Cegli, Annamaria Carissimo, Mariateresa Pizzo, Simona Casarosa, Ivan Conte, Enrico Maria Surace, Sandro BanfiMA, USA), anti-Iba1 (1:300; 019-19741; Fujifilm Wako Pure Chemical, Osaka, Japan), anti-MHCII (1:200; MCA46GA; Bio-Rad, Hercules, CA, USA), and anti-CD68 (1:500; MCA1957T; Bio-Rad, Hercules, CA, USA). Histological

(12) Angiotensin Type 1 Receptor Antagonists Protect Against Alpha-Synuclein-Induced Neuroinflammation and Dopaminergic Neuron DeathNeurotherapeutics : the journal of the American Society for Experimental NeuroTherapeuticsOctober 1, 2018Rodriguez-Perez AI, Sucunza D, Pedrosa MA, Garrido-Gil P, Kulisevsky J, Lanciego JL, Labandeira-Garcia JL.monoclonal antiserum to TH (1:10,000, T2928, Sigma) or mouse monoclonal MHC class II antibody (OX6, 1:50, MCA46G, Bio-Rad) at 4 °C in 20 mM KPBS containing 1% BSA, 2% normal serum, and 0.25% Triton X-100. The following

(13) FSGS as an Adaptive Response to Growth-Induced Podocyte StressJournal of the American Society of Nephrology : JASNOctober 1, 2017Nishizono R, Kikuchi M, Wang SQ, Chowdhury M, Nair V, Hartman J, Fukuda A, Wickman L, Hodgin JB, Bitzer M, et al.MA); ab191870 rabbit mAb; MHC Class II antibody was purchased from from AbD Serotec (Raleigh, NC); MCA46GA mouse mAb and Ki67 rabbit monoclonal antibody was purchased from Novus Biologicals (Littleton, CO) NB600–1252. Figure

(14) High-mobility group box 1 is an important mediator of microglial activation induced by cortical spreading depressionJournal of Cerebral Blood Flow & MetabolismMarch 1, 2017Tsubasa Takizawa, Mamoru Shibata, Yohei Kayama, Toshihiko Shimizu, Haruki Toriumi, Taeko Ebine, Miyuki Unekawa, Anri Koh, Akihiko Yoshimura, Norihiro Suzukiconducted immunostaining employing mouse antisera against major histocompatibility complex (MHC) class II antigen (1:500; MCA46GA; AbD Serotec, Raleigh, NC, USA) and goat antisera against cathepsin D (1:500; sc-6486; Santa Cruz Biotechnology,

(15) Glucose consumption of inflammatory cells masks metabolic deficits in the brainNeuroImageMarch 1, 2016Heiko Backes, Maureen Walberer, Anne Ladwig, Maria A. Rueger, Bernd Neumaier, Heike Endepols, Mathias Hoehn, Gereon R. Fink, Michael Schroeter, Rudolf Grafwas assessed by staining for MHC class II (clone Ox6, dilution 1:400, AbD Serotec, Oxford, UK, cat-#MCA46G). Phagocytic cells were identified with mAb ED1 (clone ED1, dilution 1:1000, AbD Serotec, Oxford, UK,

(16) Dynamics of neuroinflammation in the macrosphere model of arterio-arterial embolic focal ischemia: an approximation to human stroke patternsExperimental & Translational Stroke MedicineDecember 20, 2010Maureen Walberer, Maria A Rueger, Marie-Lune Simard, Beata Emig, Sebastian Jander, Gereon R Fink, Michael Schroeterwas assessed by staining for MHC class II (clone Ox6, dilution 1:400, AbD Serotec, Oxford, UK, cat-#MCA46G). Phagocytic cells were identified with mAb ED1 (clone ED1, dilution 1:1000, AbD Serotec, Oxford, UK,

(17) Dynamics of neuroinflammation in the macrosphere model of arterio-arterial embolic focal ischemia: an approximation to human stroke patternsExperimental & Translational Stroke MedicineDecember 20, 2010Maureen Walberer, Maria A Rueger, Marie-Lune Simard, Beata Emig, Sebastian Jander, Gereon R Fink, Michael Schroeterwas assessed by staining for MHC class II (clone Ox6, dilution 1:400, AbD Serotec, Oxford, UK, cat-#MCA46G). Phagocytic cells were identified with mAb ED1 (clone ED1, dilution 1:1000, AbD Serotec, Oxford, UK,

(18) Activated microglial cells acquire an immature dendritic cell phenotype and may terminate the immune response in an acute model of EAEJournal of NeuroimmunologyMarch 31, 2010Beatriz Almolda, Berta González, Bernardo Castellano

(19) Flt3L in combination with HSV1-TK-mediated gene therapy reverses brain tumor-induced behavioral deficits.Molecular therapy : the journal of the American Society of Gene TherapyApril 1, 2008Gwendalyn D King, Kurt M Kroeger, Catherine J Bresee, Marianela Candolfi, Chunyan Liu, Charlene M Manalo, A K M Ghulam Muhammad, Robert N Pechnick, Pedro R Lowenstein, Maria G Castro

(20) Kinetics of RANKL, RANK and OPG expressions in experimentally induced rat periapical lesionsOral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and EndodontologyNovember 22, 2006Nobuyuki Kawashima DDS PhD, Noriyuki Suzuki DDS PhD, Guangyan Yang DDS, Chie Ohi DDS, Shigeru Okuhara DDS PhD, Hiromi Nakano-Kawanishi DDS PhD, Hideaki Suda DDS PhD

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MOUSE ANTI RAT MHC CLASS II RT1B

MOUSE ANTI RAT MHC CLASS II RT1B

MOUSE ANTI RAT MHC CLASS II RT1B

MOUSE ANTI RAT MHC CLASS II RT1B

MOUSE ANTI RAT MHC CLASS II RT1B from Bio-Rad (Formerly AbD Serotec)

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MOUSE ANTI RAT MHC CLASS II RT1B from Bio-Rad (Formerly AbD Serotec)

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