FIH-1/HIF-1AN Antibody (162c)

Product Specs
ItemFIH-1/HIF-1AN Antibody (162c) - BSA Free
CompanyNovus Biologicals, a Bio-Techne Brand
Price $429.00Supplier Page View Company Product Page
Catalog NumberNBP1-30333
ImmunogenFull length human Factor Inhibiting HIF-1 protein [Swiss-Prot# Q9NWT6]
NCBI Gene AliasesFIH1
Concentration1 mg/ml
ClonalityMonoclonal
ApplicationsIF/IHC,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence
HostMouse
IsotypeIgG1
Clone162c
FormatTris-Glycine and 0.15M NaCl
Conjugate/TagUnconjugated
ReactivityHuman
Quantity0.1 ml (also 0.025 ml)
TargetFIH-1/HIF-1AN
NCBI Full Gene Namehypoxia inducible factor 1 subunit alpha inhibitor
PurityProtein G purified
Molecular Weight40 kDa
Research AreaAngiogenesis, Cancer, Chromatin Research, Hypoxia, Transcription Factors and Regulators
Antibody TypePrimary Antibodies
StorageStore at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles

Specifications/Features

Available conjugates: Unconjugated

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Novus Biologicals, a Bio-Techne Brand

United States: 10771 E Easter Ave

Centennial, Colorado 80112

United States

Phone:
303-730-1950
888-506-6887

Email: novus@novusbio.com

Company Profile

Website: https://www.novusbio.com

(1) Tankyrases modulate the hypoxia response through non-catalytic mechanisms affecting HIF-1αCell Communication and SignalingNovember 5, 2025Esteban Zamudio-Martínez, Daniel Delgado-Bellido, Jerónimo Borrego-Pérez, Angel Garcia-Diaz, Ana Belén Herrera-Campos, José Manuel Rodríguez-Vargas, F. Javier Oliverinteractions between proteins at distances < 40 nm. In our study, we detected the interaction between FIH-1 (NBP1-30333, Novus) and HIF-1α (NB100-479, Novus). Vectashield with DAPI (H1200, Vector Laboratories) was used as

(2) Oxygen-dependent bond formation with FIH regulates the activity of the client protein OTUB1Redox biologySeptember 1, 2019Pickel C, Günter J, Ruiz-Serrano A, Spielmann P, Fabrizio JA, Wolski W, Peet DJ, Wenger RH, Scholz CC.nitrocellulose membranes and detected using anti-FIH antibody (Novus Biologicals, Littleton CO, USA; NBP1-30333), anti-V5 antibody (Invitrogen; R960-025), anti-OTUB1 antibody (Cell Signaling Technology, Danvers,

(3) Prolyl hydroxylase domain protein 3 and asparaginyl hydroxylase factor inhibiting HIF-1 levels are predictive of tumoral behavior and prognosis in hepatocellular carcinomaOncotargetFebruary 21, 2017Ma M, Hua S, Li G, Wang S, Cheng X, He S, Wu P, Chen X.

(4) A DNA-binding Molecule Targeting the Adaptive Hypoxic Response in Multiple Myeloma Has Potent Antitumor ActivityMolecular cancer research : MCRMarch 1, 2016Mysore VS, Szablowski J, Dervan PB, Frost PJ.

(5) Synthetic transactivation screening reveals ETV4 as broad coactivator of hypoxia-inducible factor signalingNucleic acids researchMarch 1, 2012Wollenick K, Hu J, Kristiansen G, Schraml P, Rehrauer H, Berchner-Pfannschmidt U, Fandrey J, Wenger RH, Stiehl DP.(sdix20580002; Novus Biologicals), rabbit anti-human PHD2 (NB100-137; Novus Biologicals), mAb anti-FIH-1 (NBP1-30333; Novus Biologicals), mAb anti-p300 (554215; BD Pharmingen) and mAb anti-β-actin (clone AC-74; Sigma).

(6) Factor inhibiting HIF (FIH-1) promotes renal cancer cell survival by protecting cells from HIF-1α-mediated apoptosisBritish journal of cancerMarch 29, 2011Khan MN, Bhattacharyya T, Andrikopoulos P, Esteban MA, Barod R, Connor T, Ashcroft M, Maxwell PH, Kiriakidis S.

(7) BRCA1 tumours correlate with a HIF-1alpha phenotype and have a poor prognosis through modulation of hydroxylase enzyme profile expressionBritish journal of cancerOctober 6, 2009Yan M, Rayoo M, Takano EA, KConFab Investigators., Fox SB.

(8) Posttranslational hydroxylation of ankyrin repeats in IkappaB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH)Proceedings of the National Academy of Sciences of the United States of AmericaOctober 3, 2006Cockman ME, Lancaster DE, Stolze IP, Hewitson KS, McDonough MA, Coleman ML, Coles CH, Yu X, Hay RT, Ley SC, et al.

(9) Use of novel monoclonal antibodies to determine the expression and distribution of the hypoxia regulatory factors PHD-1, PHD-2, PHD-3 and FIH in normal and neoplastic human tissuesHistopathologyDecember 1, 2005Soilleux EJ, Turley H, Tian YM, Pugh CW, Gatter KC, Harris AL.

(10) Genetic analysis of the role of the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH) in regulating hypoxia-inducible factor (HIF) transcriptional target genes [corrected]The Journal of biological chemistryOctober 8, 2004Stolze IP, Tian YM, Appelhoff RJ, Turley H, Wykoff CC, Gleadle JM, Ratcliffe PJ.

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