The Rabbit Anti-N-Acetylglucosamine Kinase Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to NAGK. This antibody recognizes Human, and Mouse antigen. The Rabbit Anti-N-Acetylglucosamine Kinase Antibody has been shown to work in the following applications: EIA, Immunoassay, ELISA, and Western Blot.
Description
N-acetylglucosamine kinase (NAGK) converts endogenous N-acetylglucosamine (GlcNAc), a major component of complex carbohydrates, from lysosomal degradation or nutritional sources into GlcNAc 6-phosphate. NAGK belongs to the group of N-acetylhexosamine kinases and is a prominent salvage enzyme of amino sugar metabolism in mammals. The predicted 344aa NAGK protein contains the 5 sequence motifs necessary for the binding of ATP by sugar kinases. NAGK shares 91.6% amino acid similarity with mouse Nagk, for which enzyme activity is detectable in all mouse tissues examined, with highest enzymatic activity in testis. It is hypothesized that NAGK has a general role in the catabolic pathways of GlcNAc as well as of ManNAc