CUL-2 (C-4) Antibody sc-166506 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemCUL-2 (C-4) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-166506
Antibody TypePrimary Antibodies
Quantity200 µg/ml
CloneC-4
ClonalityMonoclonal
Reactivitymouse, rat, human
ApplicationsWB, IP, IF, ELISA
Conjugate/TagUnconjugated
Hostmouse
FormatPurified
NCBI Full Gene Namecullin 2
TargetCUL-2 (cullin-2)
IsotypeIgG1
NCBI Gene Aliases1300003D18Rik, 4932411N15Rik, mKIAA4106

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Feedback loop centered on MAF1 reduces blood-brain barrier damage in sepsis-associated encephalopathyCellular & molecular biology lettersJanuary 20, 2025Wei X, Jiang W, Wang Z, Li Y, Jing Y, Han Y, Huang L, Chen S.antibodies against MAF1 (1:100, sc-515614, Santa Cruz Biotechnology, Dallas, TX, USA), CUL2 (1:50, sc-166506, Santa Cruz Biotechnology), and PTEN (1:100, BM4114, Boster, Wuhan, China) at 4 °C for 12 h. Next, the

(2) Increased CSN5 expression enhances the sensitivity to lenalidomide in multiple myeloma cellsiScienceDecember 20, 2024Takumi Yamamoto, Arisu Furukawa, Yue Zhou, Nobuaki Kono, Shojiro Kitajima, Hiroto Ohguchi, Yawara Kawano, Shingo Ito, Norie Araki, Sumio Ohtsuki, et al.,Cell Signaling Technology,Cat#4995; RRID: AB_2261133 CUL2 (C-4) Mouse mAb,Santa Cruz Biotechnology,Cat#sc-166506; RRID: AB_2230072 CUL3 Rabbit pAb,Cell Signaling Technology,Cat#2759; RRID: AB_2086432 CUL4A Rabbit

(3) Intrinsic signaling pathways modulate targeted protein degradationNature CommunicationsJuly 2, 2024Yuki Mori, Yoshino Akizuki, Rikuto Honda, Miyu Takao, Ayaka Tsuchimoto, Sota Hashimoto, Hiroaki Iio, Masakazu Kato, Ai Kaiho-Soma, Yasushi Saeki, et al.(Cell Signaling Technology, #83732), anti-TRIP12 (Proteintech, #25303-1-AP), anti-CUL2 (Santa Cruz Biotechnology, sc-166506), anti-VHL (Novus Biologicals, #091504), anti-b-Actin (Santa Cruz Biotechnology, sc-47778), anti-PARG

(4) CAND1 inhibits Cullin-2-RING ubiquitin ligases for enhanced substrate specificityNature structural & molecular biologyFebruary 1, 2024Wang K, Diaz S, Li L, Lohman JR, Liu X.dilution; Cell Signaling # 2118), anti-CUL2 (Thermo Fisher Scientific # 51-1800; Santa Cruz Biotechnology sc-166506), anti-VHL (Cell Signaling # 68547), anti-ELOC (Santa Cruz Biotechnology sc-135895, 1:500 dilution),

(5) Neddylation of phosphoenolpyruvate carboxykinase 1 controls glucose metabolismCell metabolismSeptember 5, 2023Gonzalez-Rellan MJ, Fernández U, Parracho T, Novoa E, Fondevila MF, da Silva Lima N, Ramos L, Rodríguez A, Serrano-Maciá M, Perez-Mejias G, et al.Carboxylase (PC),Abcam,Cat# ab126707; RRID: AB_11130771 1:1000 Mouse monoclonal Cullin-2,Santa Cruz,Cat# sc-166506; RRID: AB_2230072 1:5000 Mouse monoclonal Glyceraldehyde 3- phosphate Dehydrogenase (GAPDH),Merck,Cat#

(6) MicroRNA-154-5p suppresses cervical carcinoma growth and metastasis by silencing Cullin2 in vitro and in vivoPeerJJanuary 1, 2023Li Y, Wei Y, Zhang H, Bai Y, Wang X, Li Q, Liu Y, Wang S, Wang J, Wen S, et al.

(7) AKTIP loss is enriched in ERα-positive breast cancer for tumorigenesis and confers endocrine resistanceCell reportsDecember 13, 2022Ng ASN, Zhang S, Mak VCY, Zhou Y, Yuen Y, Sharma R, Lu Y, Zhuang G, Zhao W, Pang HH, et al.

(8) Post-translational control of beige fat biogenesis by PRDM16 stabilizationNatureSeptember 1, 2022Wang Q, Li H, Tajima K, Verkerke ARP, Taxin ZH, Hou Z, Cole JB, Li F, Wong J, Abe I, et al.were used in this study: anti-UCP1 (ab-10983, Abcam), anti-UCP1 (U6382, Sigma-Aldrich), anti-CUL2 (sc-166506, Santa Cruz), anti-recombinant CUL2 (EPR3104(2)) (ab166917, Abcam), anti-APPBP2 (NBP2-81781, Novus),

(9) Mouse Adenovirus Type 1 E4orf6 Induces PKR DegradationJournal of virologyApril 13, 2022Tejera-Hernández B, Goodman DE, Nevarez JM, Spindler KR.

(10) Immunoexpression of HSPA9 and CUL2 in prostatic tissue and adenocarcinomaAnnals of diagnostic pathologyFebruary 1, 2022Hirth CG, Vasconcelos GR, da Cunha MDPSS, Leite CHB, Dornelas CA.

(11) Potassium Effects on NCC Are Attenuated during Inhibition of Cullin E3-Ubiquitin LigasesCellsDecember 29, 2021Murali SK, Little R, Poulsen SB, Ferdaus MZ, Ellison DH, McCormick JA, Fenton RA.(SPC-402D, StressMarq), pSPAK/OSR1 (07-2273, Millipore), SPAK/OSR1 [29], Cul1 (sc-17775, Santa Cruz), Cul2 (sc-166506, Santa Cruz), Cul3 (sc-166110, Santa Cruz), Cul4 (sc-377188, Santa Cruz), Cul5 (sc-373822, Santa Cruz),

(12) ZSWIM8 is a myogenic protein that partly prevents C2C12 differentiationScientific reportsOctober 22, 2021Okumura F, Oki N, Fujiki Y, Ikuta R, Osaki K, Hamada S, Nakatsukasa K, Hisamoto N, Hara T, Kamura T.ab12331; Abcam), poly-ubiquitin (1 μg/mL in Can Get Signal; FK2; Cosmo Bio), Cul2 (1 μg/mL in PBS; sc-166506; Santa Cruz Biotechnology), total and phosphorylated p38 MAPK (1 μg/mL in PBS; PhosphoPlus p38 MAPK (Thr180/Tyr182) Antibody Duet

(13) Selective inhibition of cullin 3 neddylation through covalent targeting DCN1 protects mice from acetaminophen-induced liver toxicityNature communicationsMay 11, 2021Zhou H, Lu J, Chinnaswamy K, Stuckey JA, Liu L, McEachern D, Yang CY, Bernard D, Shen H, Rui L, et al.control. Antibodies were purchased commercially: cullin 1 (sc-17775, 1:500 dilution) and cullin 2 (sc-166506, 1:500 dilution) from Santa Cruz Biotech (Santa Cruz, CA); cullin 4A (PA5-14542, 1:1000 dilution), cullin

(14) ORF10-Cullin-2-ZYG11B complex is not required for SARS-CoV-2 infectionProceedings of the National Academy of Sciences of the United States of AmericaApril 27, 2021Mena EL, Donahue CJ, Vaites LP, Li J, Rona G, O'Leary C, Lignitto L, Miwatani-Minter B, Paulo JA, Dhabaria A, et al.(Santa Cruz, sc-8432), anti-GAPDH (Cell Signaling, D16H11), anti-FLAG (Sigma, F1804), anti-CUL2 (Santa Cruz, sc-166506), anti-Elongin B (Santa Cruz, sc-133090), anti-Strep tag (IBA Lifesciences, 2-1507-001), anti-ACE2 (R&D Systems

(15) NRBP1-Containing CRL2/CRL4A Regulates Amyloid β Production by Targeting BRI2 and BRI3 for DegradationCell reportsMarch 10, 2020Yasukawa T, Tsutsui A, Tomomori-Sato C, Sato S, Saraf A, Washburn MP, Florens L, Terada T, Shimizu K, Conaway RC, et al.

(16) The small molecule PSSM0332 disassociates the CRL4A^DCAF8 E3 ligase complex to decrease the ubiquitination of NcoR1 and inhibit the inflammatory response in a mouse sepsis-induced myocardial dysfunction modelInternational journal of biological sciencesJanuary 1, 2020Peng Q, Xu H, Xiao M, Wang L.probed with antibodies specific to CUL1 (Santa Cruz Biotechnology, Dallas, TX, USA, #sc-17775), CUL2 (#sc-166506), CUL3 (#sc-166054), CUL4A, CUL4B, CUL5 (#373822), CUL7 (#sc-53810), CUL9 (Invitrogen, Carlsbad, CA,

(17) MicroRNA-154-5p regulates the HPV16 E7-pRb pathway in Cervical Carcinogenesis by targeting CUL2Journal of CancerJanuary 1, 2020Zhao W, Liu Y, Zhang L, Ding L, Li Y, Zhang H, Wang T, Hao M.

(18) Heterozygous deletion of chromosome 17p renders prostate cancer vulnerable to inhibition of RNA polymerase IINature communicationsOctober 22, 2018Li Y, Liu Y, Xu H, Jiang G, Van der Jeught K, Fang Y, Zhou Z, Zhang L, Frieden M, Wang L, et al.for immunoblotting and 1:200 for IHC), anti-CUL1 antibody (sc-17775, 1:1000 dilution), anti-CUL2 antibody (sc-166506, 1:1000 dilution), anti-CUL4A/4B antibody (sc-377188, 1:1000 dilution), anti-CUL5 antibody (sc-373822,

(19) C-Terminal End-Directed Protein Elimination by CRL2 Ubiquitin LigasesMolecular cellMay 17, 2018Lin HC, Yeh CW, Chen YF, Lee TT, Hsieh PY, Rusnac DV, Lin SY, Elledge SJ, Zheng N, Yen HS.

(20) Differentially expressed host long intergenic noncoding RNA and mRNA in HIV-1 and HIV-2 infectionScientific reportsFebruary 7, 2018Biswas S, Haleyurgirisetty M, Ragupathy V, Wang X, Lee S, Hewlett I, Devadas K.experiment as described earlier28 with m CUL 2 monoclonal antibody (Santa Cruz Biotechnology, Inc., Cat # sc-166506)67, RBBP4 monoclonal antibody (Santa Cruz Biotechnology, Inc., Cat # sc-373873)68 and β-Actin monoclonal

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5/9/2021Not the Best Antibody for Immunodetection of Culin2 Raj KumarHuman cells were treated with growth factor for a different period's cells were lysed in RIPA buffer, and proteins were extracted. The extracted proteins were resolved in 10% denaturing gel and ... Read Review

CUL-2 (C-4) Antibody

CUL-2 (C-4) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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CUL-2 (C-4) Antibody from Santa Cruz Biotechnology, Inc.

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