Gα q (10) Antibody sc-136181 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemGα q (10) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-136181
Antibody TypePrimary Antibodies
NCBI Gene AliasesGqI, Gq, 6230401I02Rik, Dsk10, GAQ, CMAL, 1110005L02Rik, Dsk1, CMC1, SWS, G-ALPHA-q, Galphaq
Clone10
Quantity200 µg/ml
ClonalityMonoclonal
FormatPurified
Reactivitymouse, rat, human, canine
Conjugate/TagUnconjugated
Hostmouse
ApplicationsWB, IP, IF
NCBI Full Gene Nameguanine nucleotide binding protein, alpha q polypeptide, G protein subunit alpha q
TargetGalpha q
IsotypeIgG1

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Activation of G protein‐coupled parathyroid hormone receptors in rat incisor odontoblasts promotes mineralization via cyclic adenosine monophosphate, not Ca2+ signalling: In vitro studyInternational Endodontic JournalOctober 1, 2025Natsuki Saito, Takehito Ouchi, Maki Kimura, Ryuya Kurashima, Yoshiyuki Shibukawaand mouse monoclonal anti‐heterotrimeric G‐protein α‐subunit Gαq (Gnaq) (Santa Cruz Biotechnology; sc‐136181, 1:200). For the negative control, we used mouse polyclonal IgG isotype control antibody (abcam, Cambridge,

(2) RGS2 is an innate immune checkpoint for suppressing Gαq-mediated IFNγ generation and lung injuryiScienceFebruary 21, 2025Jagdish Chandra Joshi, Bhagwati Joshi, Cuiping Zhang, Somenath Banerjee, Vigneshwaran Vellingiri, Vijay Avin Balaji Raghunathrao, Mumtaz Anwar, Tejas Pravin Rokade, Lianghui Zhang, Ruhul Amin, et al.anti-phospho-NFATC2 (Ser54, from Invitrogen # 44-944G) anti-TLR4 (Santa Cruz #sc-293072), anti-Gαq (Santa Cruz #sc-136181). All antibodies were used at 1:1000 dilutions. Anti-rabbit-IgG-HRP (1:2000 dilution) (Santa Cruz Biotechnology)

(3) The LINC01315-encoded small protein YAPer-ORF competes with PRP4k to hijack YAP signaling to aberrantly promote cell growthCell Death & DifferentiationFebruary 17, 2025Zhu Xie, Chao Li, Rui Huang, Bo Wu, Qian Huang, Zhe Zhang, Tongjin Zhao, Lingqian Wu, Chengtao Li, Jianfeng Shen, et al.Cell Signaling Technology, 1:2000 dilution), anti-PRP4K (#8577, Cell Signaling Technology, 1:2000 dilution), anti-GNAQ (#sc-136181, Santa Cruz, 1:2000 dilution), anti-GNA11 (#sc-390382, Santa Cruz, 1:2000 dilution), anti-YAP1 (#sc-101199,

(4) The Dual Role of A2aR in Neuroinflammation: Modulating Microglial Polarization in White Matter LesionseNeuroFebruary 13, 2025Chang Cheng, Wenchao Cheng, Yuhan Wang, Xiuying Chen, Lan Zhang, Yi Li, Fa Shen, Dezhi Yuan, Pian Hong, Wen Huangprotein A/G beads (Santa Cruz Biotechnology) and antibody against Gq or Gs (Santa Cruz Biotechnology, sc-136181 and sc-135914, respectively), overnight at 4°C. The immunocomplexes were washed twice with detergent

(5) The Dual Role of A2aR in Neuroinflammation: Modulating Microglial Polarization in White Matter LesionseNeuroFebruary 13, 2025Chang Cheng, Wenchao Cheng, Yuhan Wang, Xiuying Chen, Lan Zhang, Yi Li, Fa Shen, Dezhi Yuan, Pian Hong, Wen Huangprotein A/G beads (Santa Cruz Biotechnology) and antibody against Gq or Gs (Santa Cruz Biotechnology, sc-136181 and sc-135914, respectively), overnight at 4°C. The immunocomplexes were washed twice with detergent

(6) Ligand-Independent Spontaneous Activation of Purinergic P2Y6 Receptor Under Cell Culture Soft SubstrateCellsFebruary 3, 2025Akiyuki Nishimura, Kazuhiro Nishiyama, Tomoya Ito, Xinya Mi, Yuri Kato, Asuka Inoue, Junken Aoki, Motohiro Nishidawas blocked in 2% BSA in Tris-buffered saline with Tween-20 (TBS-T) and then incubated with anti-Gqα (sc-136181, Santa Cruz, Dallas, TX, USA) or anti-GAPDH (016-25523, Fujifilm Medical) antibodies overnight at 4

(7) Effects of regulator of G protein signaling 2 (RGS2) overexpression in the paraventricular nucleus on blood pressure in rats with angiotensin II-induced hypertensionFrontiers in PhysiologyJune 21, 2024Shane H. Boomer, Xuefei Liu, Hong Zhengversus a β-actin control. The following primary antibodies were used: RGS2 (sc-100761, 1:125); G⍺q (sc-136181, 1:125); G⍺s (sc-135914, 1:125); PKC⍺ (sc-8323, 1:125), PKA⍺ (sc-28315, 1:125), and β-actin (sc-398595,

(8) Regulator of G protein signaling 2 inhibits Gα(q)-dependent uveal melanoma cell growthThe Journal of biological chemistryJune 1, 2022Zhang Q, Haak AJ, Sjögren B.mouse anti-β-Actin (A2228), and rabbit anti-β-Actin (A2066) were from Millipore Sigma. Mouse anti-Gαq (sc-136181) was from Santa Cruz. Mouse anti-Glu-Glu tag (901801) was from Biolegend. Mouse anti-pERK (9106S), rabbit

(9) Structure of S1PR2-heterotrimeric G(13) signaling complexScience advancesApril 1, 2022Chen H, Chen K, Huang W, Staudt LM, Cyster JG, Li X.Gαq/13 expression level Anti-Gαq mouse monoclonal antibody (Santa Cruz Biotechnology, catalog no. sc-136181) was used for detecting the expression level of Gαq/13 protein and its mutants. Anti–β-tubulin mouse

(10) Changes in mGlu5 Receptor Signaling Are Associated with Associative Learning and Memory Extinction in MiceLife (Basel, Switzerland)March 21, 2022Teleuca AE, Alemà GS, Casolini P, Barberis I, Ciabattoni F, Orlando R, Di Menna L, Iacovelli L, Scioli MR, Nicoletti F, et al.with anti-β-actin (Sigma-Aldrich, Cat. A2228, dilution 1:1000) and anti-Gαq (Santa Cruz, USA, Cat. SC136181, dilution 1:500) monoclonal antibodies. Protein expression was detected by the chemiluminescence (ECL)

(11) Tanshinone IIA inhibits Leu27IGF-II-induced insulin-like growth factor receptor II signaling and myocardial apoptosis via estrogen receptor-mediated Akt activationEnvironmental toxicologyJanuary 1, 2022Chou SL, Ramesh S, Kuo CH, Ali A, Ho TJ, Chang KP, Hsieh DJ, Kumar VB, Weng YS, Kuo WW, et al.

(12) UM-6 induces autophagy and apoptosis via the Hippo-YAP signaling pathway in cervical cancerCancer lettersOctober 28, 2021Wang D, He J, Dong J, Wu S, Liu S, Zhu H, Xu T.

(13) Uncovering a novel role of PLCβ4 in selectively mediating TCR signaling in CD8+ but not CD4+ T cellsThe Journal of experimental medicineJuly 5, 2021Sasai M, Ma JS, Okamoto M, Nishino K, Nagaoka H, Takashima E, Pradipta A, Lee Y, Kosako H, Suh PG, et al.Tesque). Reagents For Western blot analysis, anti-PLCβ4 (sc-166131), anti-HA (sc-7392), anti-GNAQ (sc-136181), anti-ERK (sc-94), anti-p38 (sc-535), anti-JNK (sc-7345), anti-ZAP70 (sc-32760), and anti-PLCγ1 (sc-7290)

(14) LPA signaling acts as a cell-extrinsic mechanism to initiate cilia disassembly and promote neurogenesisNature communicationsJanuary 28, 2021Hu HB, Song ZQ, Song GP, Li S, Tu HQ, Wu M, Zhang YC, Yuan JF, Li TT, Li PY, et al.

(15) Anti-GPR56 monoclonal antibody potentiates GPR56-mediated Src-Fak signaling to modulate cell adhesionThe Journal of biological chemistryJanuary 1, 2021Chatterjee T, Zhang S, Posey TA, Jacob J, Wu L, Yu W, Francisco LE, Liu QJ, Carmon KS.(3700), myc-tag (clone 9E11; 2276) from Cell Signaling; Gα13 (sc-293424), Gα12 (sc-515445), and Gαq (sc-136181) from Santa Cruz Biotechnology; and paxillin (610863) from BD Biosciences. For ICC and cell-based binding

(16) Targeting Opsin4/Melanopsin with a Novel Small Molecule Suppresses PKC/RAF/MEK/ERK Signaling and Inhibits Lung Adenocarcinoma ProgressionMolecular cancer research : MCRJuly 1, 2020Wang Q, Zhang T, Chang X, Wang K, Lee MH, Ma WY, Liu K, Dong Z.

(17) Deletion of the α subunit of the heterotrimeric Go protein impairs cerebellar cortical development in miceMolecular brainJune 20, 2019Cha HL, Choi JM, Oh HH, Bashyal N, Kim SS, Birnbaumer L, Suh-Kim H.(1:1000, Santa Cruz), anti- Gαi1/2/3 (1:1000, Santa Cruz, #SC-26761), anti- Gαq (1:500, Santa Cruz, #SC-136181) and anti-Pcp2 (1:100, Santa Cruz, #SC-137064) as previously described [32]. The specific immunoreactivity

(18) G protein αq exerts expression level-dependent distinct signaling paradigmsCellular signallingJune 1, 2019Kankanamge D, Tennakoon M, Weerasinghe A, Cedeno-Rosario L, Chadee DN, Karunarathne A.incubated with the primary antibodies (Santa Cruz Biotechnology) specific for Gαs (sc-135914), Gαq (sc-136181) and α-tubulin (sc-53646), followed by the appropriate HRP-conjugated secondary antibody Cell Signal.

(19) G-protein αq gene expression plays a role in alcohol tolerance in Drosophila melanogasterBrain and neuroscience advancesJanuary 1, 2019Aleyakpo B, Umukoro O, Kavlie R, Ranson DC, Thompsett A, Corcoran O, Casalotti SO.polyclonal anti-Gαq/11 at a dilution of 1:250 (Santa Cruz Biotech. Inc., USA), mouse monoclonal anti-Gαq/11 (sc-136181; Santa Cruz Biotech) at a dilution of 1:250, anti-actin at a dilution of 1:3000 (St John’s Laboratory,

(20) Essential role of ATP6AP2 enrichment in caveolae/lipid raft microdomains for the induction of neuronal differentiation of stem cellsStem cell research & therapyMay 11, 2018Makdissy N, Haddad K, AlBacha JD, Chaker D, Ismail B, Azar A, Oreibi G, Ayoub D, Achkar I, Quilliot D, et al.

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Gα q (10) Antibody

Gα q (10) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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Gα q (10) Antibody from Santa Cruz Biotechnology, Inc.

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