MyBioSource.com's Iduronate 2-Sulfatase (IDS) Antibody is a Goat Polyclonal antibody. This antibody has been shown to work in applications such as: EIA, Immunoassay, ELISA, Immunoprecipitation, and Western Blot. The Iduronate 2-Sulfatase (IDS) Antibody was generated using IDS, and Iduronate 2-sulfatase as the antigen and it reacts with Human.
Description
Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked Mucopolysaccharidosis Type II, also known as Hunter Syndrome. Iduronate-2-sulfatase has a strong sequence homology with human arylsulfatases A, B, and C, and human glucosamine-6-sulfatase. A splice variant of this gene has been described