The efficacy and safety of cell therapies can be improved by a better understanding of the biology and the structure function relationships in the signaling pathways. How can we use this knowledge to enhance the activation and endurance of chimeric antigen receptor (CAR) T cells and natural killer (NK) cells and their downstream effects?
This Bench Tips webinar discusses the use of engineering and computational tools, along with cell-based and biochemical assays for driving targeted cell-based therapies. The speakers will share their knowledge and expertise with the community and address questions posed by the audience.
In this webinar, you will learn about:
- Understanding the differences between T cells and NK cells
- Common challenges associated with culture and characterization of these cells
- Developments in new assays and technologies for characterization of CAR T/NK cells
- Impact of structure and distribution of CARs on activity
- Best practices for designing different in vitro and in vivo assays for various measurements
- Differences when working autologous versus allogenic cells
Researchers interested in the following should attend:
- Cell and gene therapy
- Genomics
- Cell culture
- Oncology
- Personalized medicine