Lysosome Staining Kits

Lysosome staining kits are available from several suppliers to assess lysosome function within biological samples. Lysosomes are membrane-bound organelles containing hydrolytic enzymes that digest extracellular material through endocytosis and intracellular material through autophagy. Dysfunction of lysosomes occurs with aging and neurodegenerative diseases, such as Parkinson’s and Alzheimer’s. In many staining kits, dyes that are selective to acidic compartments result in accumulation in the lysosome. A lysosome perturbation agent such as chloroquine is often provided as a positive control for monitoring changes in lysosome number and volume. Kits may also come with a nuclear dye as a counterstain. Visit the lysosome staining kit suppliers for more details, including kit components and other compatible dyes.