etaluma Live Cell Imaging Systems

Live Cell Imaging Systems Live cell imaging systems and microscopes can use time-lapse photography to visualize living cells in a more natural state. While other cell imaging systems often require harsh lighting and toxic dyes, live cell imagers are not constrained to these limitations. In addition, researchers that perform this technique take measures to ensure the cells are maintained in a healthy state even while on the microscope stage. Microscopy techniques that can capture live cell images include confocal microscopy, phase contrast microscopy, fluorescent microscopy, and quantitative phase-contrast microscopy. Some features to consider when deciding on what live-cell imaging technology to purchase include detector sensitivity, desired speed of image acquisition, and specimen viability.

etaluma Live Cell Imaging Systems

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Recent Product Review

  • A Super-Resolution Approach for High-Resolution Imaging of Bacterial Cell Wall Remodeling

    My research focuses on how bacterial cells remodel their walls during growth and division, as well as how changes in wall-cutting enzymes affect antibiotic responses. I utilized the Abberior 3D STED microscope to visualize very small structures on the cell surface and to track the localization of these enzymes during cell growth. This system provided clear, high-resolution images that enhanced my understanding of how variations in enzyme activity disrupt normal cell wall organization. The Abberior 3D STED microscope enabled me to observe features of the bacterial cell wall that were completely invisible with standard confocal imaging. I could distinguish subtle changes in wall structure, identify defects in remodeling, and detect altered patterns of hydrolase activity in mutant strains. Additionally, the microscope helped me compare how cells respond to antibiotics, particularly when their remodeling enzymes are disrupted. These super-resolution images provided me with a much clearer understanding of how cell wall regulation affects cell growth, shape, and stress resistance.

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    As a bacterial geneticist studying peptidoglycan biology, I generate numerous mutants to investigate the roles of various factors that regulate bacterial peptidoglycan. As part of my research, I use the LSM 780 Confocal Laser Scanning Microscope to characterize different peptidoglycan mutants and screen for positive mutant clones. Furthermore, I analyze their precise role in cell morphogenesis by visualizing peptidoglycan-associated proteins under this microscope. Overall, for mutant screening, characterization, and localization studies, the LSM 780 has played a crucial role due to its high sensitivity, resolution, and user-friendly interface, making it an indispensable tool in my research.