Fig 1: (A) TNF-a, (B) ESM-1, (C) CRP and (D) VEGF plasma levels in response to CLP-induced sepsis measured at different time points following treatment with TQ. Data are presented as the mean ± SEM. n=10 rats/group; *P<0.05 vs. Sham; #P<0.05 vs. CLP. CLP, cecal ligation and puncture; CRP, C-reactive protein; ESM-1, endothelial cell-specific molecule-1; TQ, thymoquinone.