Fig 1: The impact of SES treatment on the degradation of Cx43 and the suppression of autophagy caused by global cerebral I/R injury. A Cx43 relative mRNA expression, B Beclin-1 relative mRNA expression, C LC-3B relative mRNA expression, and D P62 level in ng/mg protein. The data are presented as mean ± SD (n = 5). Significance a regarding the control group. Significance b regarding I/R (1/24) group. Significance c regarding I/R (1/5) group. Significance d regarding SES + I/R (1/24) group. Significance: p < 0.05, highly significance (*): p < 0.001. I/R (1/24) one-hour cerebral ischemia and 24 h reperfusion, I/R (1/5) one-hour cerebral ischemia and 5-day reperfusion, and SES sesamol