Fig 1: SYT13 and IL1F10 differentiate trauma and sepsis patients. (A) The levels of the proteins A2M, IL1F10, SYT13, and TREM1 at the early (day 0) and later stage (day 5) of the infection. (B) A comparison of the protein levels of SYT13 at high and low concentrations [+Ve; positive; from (B)] with those of A2M, IL1F10, and TREM1. (C) Comparison of the A2M, SYT13, and TREM1 and protein levels with the high and low protein levels of IL1F10 [+Ve; positive; from (B)]. Data are displayed as mean +/- SEM. Healthy (n=7); trauma and sepsis (n=23).
Fig 2: Potential biomarker panel to distinguish trauma and sepsis patients. Quantitative ELISA was used to determine the levels of A2M, IL1F10, SYT13, and TREM1 in trauma and sepsis patients at various time periods. The comparison of data was performed by one-way ANOVA, Tukey’s multiple comparison test and area under the curve (AUC) analysis were performed with 95% confidence interval, using Wilson/Brown method. Healthy (n=7); trauma ans sepsis (n=23).
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