Fig 1: The effect of pinealectomy on acid ceramidase (ASAH1) content in the hippocampus and plasma in 3-, 14-, and 18-month-old rats. Data are presented as mean ± SEM. Two-way ANOVA did not indicate a significant effect of both age and surgery for ASAH1 content in the hippocampus and plasma (p > 0.05) (A,B).