Description
Bone Morphogenetic Protein 2 is a growth factor belonging to the TGF-beta superfamily and is crucial for various developmental processes, such as cardiogenesis, neurogenesis, and osteogenesis. It promotes cartilage and bone formation by initiating the canonical BMP signaling cascade through its association with the type I receptor BMPR1A and type II receptor BMPR2. In rabbits, this protein is encoded by the BMP2 gene. miR-20a promotes bone formation by activating the BMP2/RUNX2 signaling pathway, a process that has an important role in bone defect repair in rabbits