Description
Eomesodermin serves as a transcriptional activator that is vital for development. It contributes to trophoblast differentiation and later regulates mesoderm delamination and endoderm specification during gastrulation. As a critical transcription factor in mouse embryonic development, Eomes plays a significant role across various developmental stages. It is essential for the formation of the axial and body surface endoderm in early embryogenesis. In mouse embryos, Eomes expression begins in the posterior germ layer at embryonic day 5.5 (E5.5) and continues in the blastoderm, particularly in the posterior region, at embryonic day 7.5 (E7.5)