Fig 1: Evaluating the safety profile of microcapsule delivery for localized immunomodulation in healthy Yucatan Pigs.A) Demonstration of capsule delivery in pig cadaver lungs. Capsules were dyed blue for visualization B-C) Quantification of bronchoalveolar lavage (BAL) fluid and plasma concentrations of IL-1Ra and IL-10 before instillation, two days after, and at euthanasia on day 28 D) Triglycerides, Total Cholesterol, and Glucose blood levels on days 0, 2, and 28, showing no significant change. E) Albumin blood levels as a marker of liver function showing no significant change. F) Saturation of peripheral oxygen and end-tidal carbon dioxide at the start and end of each procedure G) H&E-stained sections of the lung. Scale bar, 2 mm and inset, 200 mm. Data represented as mean ± SEM (n=3).