Fig 1: PGK1 silencing inhibited microglia M1 polarization, inflammation, and glycolysis in rats with MCAO. A Neurological score, B hematoxylin and eosin staining, C MPO activity, D mRNA levels of iNOS and IL-1β, E TNF-α and IL-6 concentrations, F LDH content, G PGK1 mRNA levels, and H, I PGK1, PKM2, and LDHA protein levels in brain tissues from rats with MCAO. ***p < 0.001 vs. control; ##p < 0.01, ###p < 0.001 vs. MCAO + shNC