Fig 1: The concentration of IL-6, TSLP, and TGF-β in plasma. Data presented as the mean ± SD. CRSsNP—chronic rhinosinusitis without nasal polyposis; CRSwNP—chronic rhinosinusitis with nasal polyposis; IL-6—interleukin 6; TGF-β—transforming growth factor β; TSLP—thymic stromal lymphopoietin. CRSsNP n = 15; CRSwNP n = 15; control group n = 10. Lines connect comparison groups with a p-value denoting the significant difference and pair-wise comparisons. Statistical analysis between investigated groups—two-sided Mann–Whitney U test (independent data).
Fig 2: (A) Correlation between eosinophil count and SNOT-22 score in CRSwNP group; (B) correlation between fibronectin gene expression and WBC count in CRSwNP group; (C) correlation between periostin gene expression and TSLP level in CRSwNP group; (D) correlation between collagen I gene expression and TSLP level in CRSwNP group; (E) correlation between collagen III gene expression and TSLP level in CRSwNP group; (F) correlation between TIMP-2 gene expression and SNOT-22 score in CRSwNP group; (G) correlation between fibronectin gene expression and SNOT-22 score in CRSwNP group. SNOT-22—sinonasal outcome test; TIMP-2—tissue inhibitor of metalloproteinases 2; TSLP thymic stromal lymphopoietin; WBC—white blood cells. Gene expression data are presented as ΔΔCt, with lower ΔΔCt values indicating higher gene expression. CRSwNP n = 15. Statistical analysis—Spearman r test and nonlinear regression.
Supplier Page from Bioss Inc. for Human TSLP ELISA Kit