Fig 1: The results of SMR. (A) Venn plot of the positive result of 4 salivary flora, Cathepsin H and MI for SMR; (B) Venn plot of the positive result of Cathepsin H and MI for SMR by eQTL source; (C) The SMR locus plots for correlations of CTSH in coronary artery gene expression with Cathepsin H and MI; (D) Venn plot of the positive result of Cathepsin H and MI for SMR by pQTL source; (E) The SMR locus plots for correlations of MST1 in protein level expression with Cathepsin H and MI. CTSH = Cathepsin H, eQTL = expression Quantitative Trait Locus, MI = myocardial infarction, MR = Mendelian randomization, SMR = sample Mendelian randomization, pQTL = protein Quantitative Trait Locus.
Fig 2: Results of external validation. (A) The mRNA level expression of CTSH was detected using RT-PCR. (B) Protein level expression of Cathepsin H in serum using ELISA. (C) The mRNA level expression of MST1 was detected using RT-PCR. (D) Protein level expression of MST1 in serum using ELISA. CTSH = Cathepsin H, ELISA = enzyme-linked immunoassays, mRNA = messenger ribonucleic acid, RT-PCR = reverse transcription polymerase chain reaction.
Supplier Page from Fine Biotech Co., Ltd. for Human CTSH (Cathepsin H) ELISA Kit