Fig 1: Reference receiver operating characteristic curve for serum PNX-14 in diagnosing central precocious puberty.
Fig 2: The effects of phoenixin (PNX) at various levels of the gonadal axis. PNX binds to GPR173, activating the cyclic adenosine monophosphate/protein kinase A pathway and increasing CREB phosphorylation, thereby mediating biological functions. At the hypothalamic, PNX enhances the synthesis and secretion of gonadotropin-releasing hormone. At the pituitary, PNX increases the synthesis of gonadotropin-releasing hormone receptor and upregulates the expression of gonadotropins in pituitary gonadotrope cells. At the ovary, PNX promotes the production of estradiol and follicular maturation.
Supplier Page from Fine Biotech Co., Ltd. for Human PNX-20 (Phoenixin-20) ELISA Kit