PowerPlex 16 HS System DC2100 from Promega

Product Specs
ItemPowerPlex 16 HS System
CompanyPromega
Price Supplier Page View Company Product Page
Catalog NumberDC2100
Quantity400 reactions

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Promega

2800 Woods Hollow Rd

Madison, WI 53711

United States

Phone: Tel: +1 (608) 274-4330
Fax: +1 (608) 277-2516

Email: custserv@promega.com
techserv@promega.com

Company Profile

Website: http://www.promega.com

(1) Effects of combination therapy of a CDK4/6 and MEK inhibitor in diffuse midline glioma preclinical modelsPLoS OneDecember 22, 2025Yusuke Tomita, Gabrielle Link, Yi Ge, Emma R. H. Gold, Anna Racanelli, Herminio Joey Cardona, Megan Romero, Samantha Gadd, Jun Watanabe, Eita Uchida, et al.cultured as previously described. Short tandem repeat (STR), using the Powerplex16HS System (Promega DC2101), was obtained to confirm the identity of the cell lines. All cells were cultured in an incubator at

(2) Epithelioid Mesothelioma Cells Exhibit Increased Ferroptosis Sensitivity Compared to Non-Epithelioid Mesothelioma CellsCancers (Basel)December 13, 2025Tatsuhiro Sato, Ikue Hasegawa, Haruna Ikeda, Taichi Ohshiro, Lisa Kondo-Ida, Satomi Mukai, Satoshi Ohte, Tohru Maeda, Yoshitaka Sekidoshort-tandem repeat analysis using the PowerPlex 16 HS System (Promega, Madison, WI, USA, catalog no. DC2101). Brefeldin A (BFA) was purchased from Cell Signaling Technology (catalog no. 9972). RSL3 (catalog no.

(3) A human induced pluripotent stem cell toolbox for studying sex chromosome effectsStem Cell ReportsNovember 11, 2025Ruta Meleckyte, Wazeer Varsally, Jasmin Zohren, Jerry Eriksson, Tania Incitti, Linda Starnes, Amy Pointon, Ryan Hicks, Benjamin E. Powell, James M.A. TurnerDNAs from the parental fibroblast sample and iPSC lines using the Powerplex 16 HS System (Promega, DC2101). Analysis was done using Applied Biosystems 3500XL genetic analyzer. All lines were sent regularly

(4) Differential Efficacy of Bevacizumab and Erlotinib in Preclinical Models of Renal Medullary Carcinoma and Fumarate Hydratase–Deficient Renal Cell CarcinomaMolecular Cancer TherapeuticsNovember 3, 2025Niki M. Zacharias, Manuel Ozambela, Menuka Karki, Rong He, Pankaj K. Chauhan, Pedro I. Pesquera, Andres E. Hernandez Hernandez Gonzalez, Oscar Ochoa, Alberto Pieretti, Huiqin Chen, et al.microliters of DNA at a concentration of around 30 ng/ul was assayed using the Promega Powerplex 16 HS kit (DC2100, Promega, Madison, WI, USA) that screens 16 separate loci using PCR. All STR profiles were matched to

(5) An Annotated Biobank of Triple-Negative Breast Cancer Patient-Derived Xenografts Features Treatment-Naïve and Longitudinal Samples during Neoadjuvant ChemotherapyCancer ResearchNovember 3, 2025Amanda L. Rinkenbaugh, Yuan Qi, Shirong Cai, Jiansu Shao, Faiza Baameur Hancock, Sabrina L. Jeter-Jones, Xiaomei Zhang, Emily Powell, Lei Huo, Rosanna Lau, et al.Cytogenetics and Cell Authentication Core. The STR profiles from Promega 16 High Sensitivity STR Kit (Catalog# DC2100) analyses were compared to commercial databases (DSMZ/ATCC/JCRB/RIKEN) of approximately 2500 known profiles,

(6) SIRT2 Regulates the SMARCB1 Loss-Driven Differentiation Block in ATRTMolecular cancer research : MCRJune 3, 2025Alimova I, Wang D, DeSisto J, Danis E, Lakshmanachetty S, Prince E, Murdock G, Pierce A, Donson A, Balakrishnan I, et al.University of Colorado Molecular Biology Service Center utilizing the STR DNA Profiling PowerPlex-16 HS Kit (DC2101, Promega). Mycoplasma testing was performed routinely using Mycoplasma Detection Kit MP0035 optimized

(7) Impact of Co-mutations and Transcriptional Signatures in Non–Small Cell Lung Cancer Patients Treated with Adagrasib in the KRYSTAL-1 TrialClinical Cancer ResearchMarch 17, 2025Marcelo V. Negrao, Alvaro G. Paula, David Molkentine, Laura Hover, Monique Nilsson, Natalie Vokes, Lars Engstrom, Andrew Calinisan, David M. Briere, Laura Waters, et al.short tandem repeat (STR) DNA fingerprinting using the Promega 16 High Sensitivity STR Kit (catalog # DC2100). The STR profiles were compared with online search databases (DSMZ/ATCC/JCRB/RIKEN) of approximately

(8) Three-dimensional analysis of mitochondria in a patient-derived xenograft model of triple negative breast cancer reveals mitochondrial network remodeling following chemotherapy treatmentsbioRxivSeptember 12, 2024Mariah J. Berner, Heather K. Beasley, Zer Vue, Audra Lane, Larry Vang, Mokryun L. Baek, Andrea G. Marshall, Mason Killion, Faben Zeleke, Bryanna Shao, et al.DNA fingerprinting on DNA extracted from PDX tumors. The Promega 16 High Sensitivity STR Kit (Catalog # DC2100) was used for fingerprinting analysis, and profiles were compared to online databases (DSMZ/ ATCC/ JCRB/

(9) Centrosome amplification primes ovarian cancer cells for apoptosis and potentiates the response to chemotherapyPLOS BiologySeptember 5, 2024Frances Edwards, Giulia Fantozzi, Anthony Y. Simon, Jean-Philippe Morretton, Aurelie Herbette, Andrea E. Tijhuis, Rene Wardenaar, Stacy Foulane, Simon Gemble, Diana C.J. Spierings, et al.Cell cultures underwent authentication by short tandem repeat analysis (powerplex16 HS kit, Promega #DC2101) and were routinely checked for mycoplasma (PlasmoTest Mycoplasma detection kit, InvivoGen, #rep-pt1). Cell

(10) BET bromodomain inhibition potentiates radiosensitivity in models of H3K27-altered diffuse midline gliomaJournal of Clinical InvestigationJuly 1, 2024Jun Watanabe, Matthew R. Clutter, Michael J. Gullette, Takahiro Sasaki, Eita Uchida, Savneet Kaur, Yan Mo, Kouki Abe, Yukitomo Ishi, Nozomu Takata, et al.(Invitrogen), 10 ng/mL human EGF, and 2 μg/mL heparin. We used the PowerPlex 16 HS System (Promega DC2101) to analyze short tandem repeats (STRs) in order to confirm the identity of the cell lines. All cells

(11) Rapid P-TEFb-dependent transcriptional reorganization underpins the glioma adaptive response to radiotherapyNature CommunicationsMay 30, 2024Faye M. Walker, Lays Martin Sobral, Etienne Danis, Bridget Sanford, Sahiti Donthula, Ilango Balakrishnan, Dong Wang, Angela Pierce, Sana D. Karam, Soudabeh Kargar, et al.University of Colorado Molecular Biology Service Center utilizing the STR DNA Profiling PowerPlex-16 HS Kit (DC2101, Promega)(Supplementary Data 5). Plasmid and lentiviral production HEK293FT cells were used to produce

(12) Transcriptomic, Proteomic, and Genomic Mutational Fraction Differences Based on HPV Status Observed in Patient-Derived Xenograft Models of Penile Squamous Cell CarcinomaCancersMarch 6, 2024Zacharias NM, Segarra L, Akagi K, Fowlkes NW, Chen H, Alaniz A, de la Cerda C, Pesquera P, Xi Y, Wang J, et al.microliters of DNA at a concentration of around 30 ng/μL was assayed using the Promega Powerplex 16 HS kit (DC2100, Promega, Madison, WI, USA) that screens separate loci using PCR. All STR profiles were matched to public

(13) SETD2 Loss and ATR Inhibition Synergize to Promote cGAS Signaling and Immunotherapy Response in Renal Cell CarcinomaClinical Cancer ResearchOctober 2, 2023Xian-De Liu, Yan-Ting Zhang, Daniel J. McGrail, Xuesong Zhang, Truong Lam, Anh Hoang, Elshad Hasanov, Ganiraju Manyam, Christine B. Peterson, Haifeng Zhu, et al.short tandem repeat (STR) DNA fingerprinting using the Promega 16 High Sensitivity STR Kit (catalog # DC2100). Human RCC cell lines and Renca cells were maintained in DMEM containing 10% fetal bovine serum at

(14) A new tumorgraft panel to accelerate precision medicine in prostate cancerFrontiers in OncologyMay 26, 2023Claire Béraud, Nadege Bidan, Myriam Lassalle, Hervé Lang, Véronique Lindner, Clémentine Krucker, Julien Masliah-Planchon, Eric Potiron, Philippe Lluel, Thierry Massfelder, et al.and corresponding PDX DNA samples were subjected to STR using PowerPlex® 16 HS System (Promega, ref DC2101) that amplifies 16 STR loci and the amelogenin gender-determining marker, according to manufacturer’s

(15) Neddylation inhibition sensitises renal medullary carcinoma tumours to platinum chemotherapyClinical and translational medicineMay 1, 2023Shapiro DD, Zacharias NM, Tripathi DN, Karki M, Bertocchio JP, Soeung M, He R, Westerman ME, Gao J, Rao P, et al.maintained patient‐derived tumour tissue using the Promega 16 High Sensitivity STR Kit (catalogue #DC2100) 25 (Supporting Information S1). A second PDX model (RMC32X) was developed in a similar fashion. RMC32X

(16) Predictors of success in establishing orthotopic patient-derived xenograft models of triple negative breast cancernpj Breast CancerJanuary 10, 2023Gloria V. Echeverria, Shirong Cai, Yizheng Tu, Jiansu Shao, Emily Powell, Abena B. Redwood, Yan Jiang, Aaron McCoy, Amanda L. Rinkenbaugh, Rosanna Lau, et al.Support Grant-funded NCI # CA016672). The STR profiles from Promega 16 High Sensitivity STR Kit (cat# DC2100) analyses were compared to commercial databases (DSMZ/ATCC/JCRB/RIKEN) of ~2500 known profiles, as well

(17) A catalog of numerical centrosome defects in epithelial ovarian cancersEMBO molecular medicineSeptember 7, 2022Morretton JP, Simon A, Herbette A, Barbazan J, Pérez-González C, Cosson C, Mboup B, Latouche A, Popova T, Kieffer Y, et al.#rep‐pt1) and underwent cell authentification by short tandem repeat analysis (powerplex16 HS kit, Promega #DC2101) processed at the Genomics Platform (Department of Translational Research, Institut Curie). Immunofluorescence

(18) PLK4 is upregulated in prostate cancer and its inhibition reduces centrosome amplification and causes senescenceThe ProstateJune 1, 2022Singh CK, Denu RA, Nihal M, Shabbir M, Garvey DR, Huang W, Iczkowski KA, Ahmad N.conditions. The cell lines were authenticated by STR analysis using Promega PowerPlex 16HS System Kit (DC2101) at the University of Wisconsin Translational Research Initiatives in Pathology) laboratory. These cells

(19) Experimental models of undifferentiated pleomorphic sarcoma and malignant peripheral nerve sheath tumorLaboratory InvestigationJune 1, 2022Angela D. Bhalla, Sharon M. Landers, Anand K. Singh, Jace P. Landry, Michelle G. Yeagley, Gabryella S.B. Myerson, Cristian B. Delgado-Baez, Stephanie Dunnand, Theresa Nguyen, Xiaoyan Ma, et al.CA). Short tandem repeat (STR) DNA profiling was performed using a Powerplex 16 HS kit (Promega, cat # DC2101). Genomic DNA was extracted from the tumor specimens and the cultured cell lines using a QIAmp mini

(20) Therapeutic Targeting of EZH2 and BET BRD4 in Pediatric Rhabdoid TumorsMolecular Cancer TherapeuticsMay 4, 2022Yukitomo Ishi, Yongzhan Zhang, Ali Zhang, Takahiro Sasaki, Andrea Piunti, Amreena Suri, Jun Watanabe, Kouki Abe, Xingyao He, Hiroaki Katagi, et al.STEMCELL Technologies, Vancouver, Canada). Short tandem repeat (STR) analysis using the Powerplex16HS System (DC2101; Promega, Madison, WI, USA) was used to confirm the identity of the cell lines. Modification of tumor

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PowerPlex 16 HS System

PowerPlex 16 HS System from Promega

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PowerPlex 16 HS System from Promega

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