Description
Product Characteristics: For the quantitative determination of human plasma protease C1 inhibitor (SERPING1) concentrations in serum, plasma, tissue homogenates.
Target Information: This gene encodes a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its protein inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE). Alternative splicing results in multiple transcript variants encoding the same isoform. [provided by RefSeq, Jul 2008]