Fig 1: RAS but not blood pressure is affected in adult offspring of sham and RIAKI parents. (A) In 12-week-old offspring, AngII kidney tissue content varied by breeding pairing and (B) offspring sex. Females from sham pairings had higher AngII levels than males; female offspring of RIAKI had lower AngII levels than sham females. However, (C) systolic and (D) diastolic blood pressures of 6-month-old offspring were not significantly different. T-test for two groups and one-way ANOVA with post hoc tests. *: p < 0.05.