Fig 1: The combination treatment of DOX and CUR against H69AR cells after 24 h treatment. (a) NFKB, (b) p-STAT3, (c) GPX4, (d) Nrf2, and (e) MRP1. Cells were treated with DOX and/or CUR at the following concentrations: DOX IC10 = 9.2 µM, IC20 = 20.8 µM, IC30 = 35.6 µM; CUR IC10 = 8.5 µM, IC20 = 19.2 µM, IC30 = 32.9 µM. Data are expressed as mean ± SD (n = 3 independent experiments). * Significantly different at p < 0.05 (Tukey post hoc test).